Inflammation associated with nerve injury produces a number of pathogenic chemical
mediators of which prostanoids are a potent component. Cyclooxygenases (Cox‐1 and Cox …

Recent evidence suggested that cyclooxygenase-2 (COX-2) expression in the peripheral
nerve early after nerve injury might be involved in the development of neuropathic pain …

We previously reported the up-regulation of cyclooxygenase 2 (COX2) in injured sciatic
nerve of rats with partial sciatic nerve ligation (PSNL) and the reversal of PSNL-elicited …

Acute inflammation following spinal cord injury results in secondary injury and pathological
reorganisation of the central nervous system (CNS) architecture. Cyclooxygenases …

Abstract CYCLOOXYGENASE-2 (COX-2) is considered to play a major role in inflammation
processes by catalyzing the production of prostaglandins (PGs). Using in situ hybridization …

Cyclooxygenase, or prostaglandin G/H synthase, is the rate-limiting step in the production of
prostaglandins. A new isoform, cyclooxygenase-2 (COX-2), has been cloned that is induced …

The expression of both cyclooxygenase (COX)‐1 and COX‐2, which are representative
enzymes in prostaglandin synthesis, was evaluated in the sciatic nerve of rats with …

Inflammatory cellular responses to brain injury are promoted by proinflammatory
messengers. Cyclooxygenases (prostaglandin endoperoxide H synthases [PGH]) are key …

Object. Secondary damage after central nervous system (CNS) injury is driven in part by
oxidative stress and CNS inflammation and is substantially mediated by cyclooxygenases …

Background Recent studies show that inflammatory processes may contribute to
neuropathic pain. Cyclooxygenase-2 (Cox-2) is an inducible enzyme responsible for …