Mucin core peptide expression can help differentiate Barrett's esophagus from intestinal metaplasia of the stomach

JN Glickman, A Shahsafaei… - The American journal of …, 2003 - journals.lww.com
It is important to distinguish Barrett's esophagus (BE) from intestinal metaplasia related to
carditis because these conditions have a different natural history, risk of malignancy, and …

Cytokeratin 7/20 and MUC1, 2, 5AC, and 6 expression patterns in Barrett's esophagus and intestinal metaplasia of the stomach: intestinal metaplasia of the cardia is …

C Gulmann, O Al Shaqaqi, A Grace… - Applied …, 2004 - journals.lww.com
Intestinal metaplasia (IM) in endoscopic biopsies obtained from close to the
gastroesophageal junction may represent IM of the cardia (CIM) or Barrett's esophagus (BE) …

Mucin core polypeptide expression in the progression of neoplasia in Barrett's esophagus

JN Glickman, PL Blount, CA Sanchez, DS Cowan… - Human pathology, 2006 - Elsevier
We have previously demonstrated a specific pattern of mucin (MUC) core polypeptide
expression in Barrett's esophagus (BE) characterized by MUC1 and MUC6 positivity in …

Clinical impact of MUC1 and MUC4 expression in Barrett-associated oesophageal adenocarcinoma

G Piessen, A Wacrenier, N Briez, JP Triboulet… - Journal of clinical …, 2009 - jcp.bmj.com
Aims: To study the expression of MUC1 and MUC4 mucins in Barrett-associated
oesophageal adenocarcinoma and coexisting lesions of the carcinogenic sequence (normal …

Gastric and intestinal differentiation in Barrett's metaplasia and associated adenocarcinoma

P Chaves, C Cruz, A Dias Pereira… - Diseases of the …, 2005 - academic.oup.com
Intestinal metaplasia is a prerequisite criterion for the diagnosis of Barrett's metaplasia and
the sole columnar esophageal lining associated with malignancy. It is recognized by the …

Mucin pattern reflects the origin of the adenocarcinoma in Barrett's esophagus: a retrospective clinical and laboratorial study

S Szachnowicz, I Cecconello, U Ribeiro, K Iriya… - World journal of surgical …, 2009 - Springer
Background Mucin immunoexpression in adenocarcinoma arising in Barrett's esophagus
(BE) may indicate the carcinogenesis pathway. The aim of this study was to evaluate …

Gastric‐type mucin and TFF‐peptide expression in Barrett's oesophagus is disturbed during increased expression of MUC2

JHB Van de Bovenkamp… - …, 2003 - Wiley Online Library
Aims: Barrett's oesophagus constitutes metaplastic epithelium, often diagnosed by mucin
histochemistry. We determined the mucins and trefoil factor family (TFF)‐peptides that were …

Barrett's esophagus is characterized by expression of gastric-type mucins (MUC5AC, MUC6) and TFF peptides (TFF1 and TFF2), but the risk of carcinoma …

C Warson, JHB Van de Bovenkamp… - Human pathology, 2002 - Elsevier
Barrett's esophagus (BE) consists of metaplastic epithelium of the esophagus, generally
diagnosed by mucin histochemistry. We aimed to determine which mucins were expressed …

Mucin expression in the esophageal malignant and pre-malignant states: a systematic review and meta-analysis

Y Niv, SB Ho, R Fass, T Rokkas - Journal of clinical …, 2018 - journals.lww.com
Background: Mucins are heavily glycosylated glycoproteins, synthesized by mucosal
surfaces and have an important role in healthy state and malignant diseases. Change in …

Mucin gene expression in Barrett's oesophagus: an in situ hybridisation and immunohistochemical study

GS Arul, M Moorghen, N Myerscough, DA Alderson… - Gut, 2000 - gut.bmj.com
BACKGROUND AND AIMS Mucin genes are expressed in a site specific manner throughout
the gastrointestinal tract. Little is known about the expression pattern in the oesophagus. In …