Can molecular mimicry explain the cytokine storm of SARS‐CoV‐2?: An in silico approach

G Obando‐Pereda - Journal of medical virology, 2021 - Wiley Online Library
PARP14 and PARP9 play a key role in macrophage immune regulation. SARS‐CoV‐2 is an
emerging viral disease that triggers hyper‐inflammation known as a cytokine storm. In this …

[HTML][HTML] The possible role of molecular mimicry in SARS-CoV-2-mediated autoimmunity: an immunobiochemical basis

D Kovačić, J Jotanović, J Laković - Journal of Medical Science, 2021 - jms.ump.edu.pl
Abstract Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute
Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), persists as a threat to global health …

[HTML][HTML] Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein

T Haystead, E Lee, K Cho, G Gullickson, P Hughes… - Scientific Reports, 2023 - nature.com
Evidence in SARS-CoV-2 patients have identified that viral infection is accompanied by the
expression of inflammatory mediators by both immune and stromal cells within the …

Comparative analysis of non structural protein 1 of SARS-CoV2 with SARS-CoV1 and MERS-CoV: An in silico study

A Chaudhuri - Journal of Molecular Structure, 2021 - Elsevier
The recently emerged SARS-CoV2 caused a major pandemic of coronavirus disease
(COVID-19). Non structural protein 1 (nsp1) is found in all beta coronavirus that cause …

[HTML][HTML] SARS-CoV-2 nsp1: bioinformatics, potential structural and functional features, and implications for drug/vaccine designs

YQ Min, Q Mo, J Wang, F Deng, H Wang… - Frontiers in …, 2020 - frontiersin.org
The emerging coronavirus disease (COVID-19) caused by SARS-CoV-2 has led to social
and economic disruption globally. It is urgently needed to understand the structure and …

Immunoinformatic analysis of structural and epitope variations in the spike and Orf8 proteins of SARS‐CoV‐2/B. 1.1. 7

M Hussain, S Shabbir, A Amanullah… - Journal of medical …, 2021 - Wiley Online Library
A newly emerged strain of SARS‐CoV‐2 of B. 1.1. 7 lineage has caused a significant surge
in the SARS‐CoV‐2 infections in the UK. In this study, changes in the epitopes of spike and …

SARS‐CoV‐2 infection‐induced immune responses: Friends or foes?

K Li, Z Hao, X Zhao, J Du, Y Zhou - Scandinavian Journal of …, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is an emerging
coronavirus that belongs to the β‐genus, causing the outbreak of coronavirus disease 19 …

[HTML][HTML] Bioinformatics prediction of B and T cell epitopes within the spike and nucleocapsid proteins of SARS-CoV2

RM Dawood, MA El-Meguid, GM Salum… - Journal of infection and …, 2021 - Elsevier
Background The striking difference in severity of SARS CoV2 infection among global
population is partly attributed to viral factors. With the spike (S) and nucleocapsid (N) are the …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells

XY Yang, T Liu, SC Jiang, ZW Zhang, YF Fu, ZL Li… - Vaccine, 2024 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) vaccines protect the public and limit viral
spread. However, inactivated viral vaccines use the whole virus particle, which contains …