[HTML][HTML] Immune characteristics analysis reveals two key inflammatory factors correlated to the expressions of SARS-CoV-2 S1-specific antibodies

S Li, W Wang, T Li, X Han, C Hu, Y Wang, M Shen… - Genes & …, 2022 - Elsevier
The pandemic of COVID-19 caused by SARS-CoV-2 has made serious threats to the public
health. Antibodies have been considered as promising therapeutics for the prevention and …

Genome-wide analysis of protein–protein interactions and involvement of viral proteins in SARS-CoV-2 replication

Y Jiang, K Tong, R Yao, Y Zhou, H Lin, L Du, Y Jin… - Cell & Bioscience, 2021 - Springer
Background Analysis of viral protein–protein interactions is an essential step to uncover the
viral protein functions and the molecular mechanism for the assembly of a viral protein …

[HTML][HTML] Distinct molecular mechanisms characterizing pathogenesis of SARS-CoV-2

SJ Lee, YJ Kim, DG Ahn - Journal of Microbiology and …, 2022 - ncbi.nlm.nih.gov
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
continued for over 2 years, following the outbreak of coronavirus-19 (COVID-19) in 2019. It …

Global variation in SARS-CoV-2 proteome and its implication in pre-lockdown emergence and dissemination of 5 dominant SARS-CoV-2 clades

LPP Patro, C Sathyaseelan, PP Uttamrao… - Infection, Genetics and …, 2021 - Elsevier
SARS-CoV-2 is currently causing major havoc worldwide with its efficient transmission and
propagation. To track the emergence as well as the persistence of mutations during the early …

[HTML][HTML] Immune responses in SARS-CoV-2, SARS-CoV, and MERS-CoV infections: a comparative review

S Irani - International journal of preventive medicine, 2022 - journals.lww.com
Coronavirus, discovered in the 1960s, is able to infect human hosts and causes mild to
serious respiratory problems. In the last two decades, the severe acute respiratory syndrome …

A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response

Y Zhao, L Sui, P Wu, W Wang, Z Wang, Y Yu… - … and Targeted Therapy, 2021 - nature.com
The recently emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of ongoing global pandemic of COVID-19, may trigger …

The analysis on the human protein domain targets and host-like interacting motifs for the MERS-CoV and SARS-CoV/CoV-2 infers the molecular mimicry of …

YA Martínez, X Guo, DP Portales-Pérez, G Rivera… - PLoS …, 2021 - journals.plos.org
The MERS-CoV, SARS-CoV, and SARS-CoV-2 are highly pathogenic viruses that can
cause severe pneumonic diseases in humans. Unfortunately, there is a non-available …

[PDF][PDF] Dysregulation of the immune system as a driver of the critical course of novel coronavirus disease 2019

A Kosmaczewska, I Frydecka - Pol Arch Intern Med, 2020 - scholar.archive.org
AbsTRACT Novel coronavirus disease 2019 (COVID‑19) is a highly contagious, respiratory
disease caused by the newly emerged severe acute respiratory syndrome coronavirus 2 …

The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection

D Lécuyer, R Nardacci, D Tannous… - Frontiers in …, 2023 - frontiersin.org
Purinergic receptors and NOD-like receptor protein 3 (NLRP3) inflammasome regulate
inflammation and viral infection, but their effects on severe acute respiratory syndrome …

SARS-CoV-2 Nsp5 protein causes acute lung inflammation, a dynamical mathematical model

A Bensussen, ER Álvarez-Buylla, J Díaz - Frontiers in Systems …, 2021 - frontiersin.org
In the present work we propose a dynamical mathematical model of the lung cells
inflammation process in response to SARS-CoV-2 infection. In this scenario the main …