[PDF][PDF] A Transcriptome analysis identifies potential preventive and therapeutic approaches towards COVID-19

MR Islam, A Fischer - 2020 - researchgate.net
The recent outbreak of Coronavirus Disease 2019 (COVID-19) is a major threat to human 20
health and the global economy. In addition to the development of vaccines there is an 21 …

[HTML][HTML] Identification of key differentially expressed genes in SARS-CoV-2 using RNA-seq analysis with a systems biology approach

A Safarzadeh, BM Hussen, M Taheri, S Ghafouri-Fard… - Cytokine, 2023 - Elsevier
COVID-19 is associated with dysregulation of several genes and signaling pathways. Based
on the importance of expression profiling in identification of the pathogenesis of COVID-19 …

SARS-CoV-2 infection initiates interleukin-17-enriched transcriptional response in different cells from multiple organs

MZ Hasan, S Islam, K Matsumoto, T Kawai - Scientific reports, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has emerged as a
pandemic. Paucity of information concerning the virus and therapeutic interventions have …

Molecular signatures in the progression of COVID-19 severity

R De, RK Azad - Scientific Reports, 2022 - nature.com
SARS-CoV-2 is the causative agent of COVID-19 that has infected over 642 million and
killed over 6.6 million people around the globe. Underlying a wide range of clinical …

Comprehensive characterization of the transcriptional response to COVID-19 in multiple organs reveals shared signatures across tissues

COVID Tissue Atlas Consortium, AA Granados… - bioRxiv, 2022 - biorxiv.org
Abstract Infection by Coronavirus SARS-CoV2 is a severe and often deadly disease that has
implications for the respiratory system and multiple organs across the human body. While …

Dual RNA-Seq analysis of SARS-CoV-2 correlates specific human transcriptional response pathways directly to viral expression

ND Maulding, S Seiler, A Pearson, N Kreusser… - Scientific reports, 2022 - nature.com
The SARS-CoV-2 pandemic has challenged humankind's ability to quickly determine the
cascade of health effects caused by a novel infection. Even with the unprecedented speed at …

[HTML][HTML] Integration and reanalysis of four RNA-seq datasets including BALF, nasopharyngeal swabs, lung biopsy, and mouse models reveals common immune …

R Alberts, SC Chan, QF Meng, S He, L Rao, X Liu… - Immune …, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2), has spread over the world causing a pandemic …

[PDF][PDF] Single-nuclei characterization of pervasive transcriptional signatures across organs in response to COVID-19

H Song, A Agrawal, AT Chen, T Peng, N Neff, AO Pisco… - scienceopen.com
Background: Infection by coronavirus SARS-CoV2 is a severe and often deadly disease that
has implications for the respiratory system and multiple organs across the human body …

Gene expression profiling of SARS-CoV-2 infections reveal distinct primary lung cell and systemic immune infection responses that identify pathways relevant in …

MA Moni, JMW Quinn, N Sinmaz… - Briefings in …, 2021 - academic.oup.com
To identify key gene expression pathways altered with infection of the novel coronavirus
SARS-CoV-2, we performed the largest comparative genomic and transcriptomic analysis to …

Integrated analysis of RNA-seq datasets reveals novel targets and regulators of COVID-19 severity

TT Oliveira, JF Freitas, VPB de Medeiros… - Life Science …, 2024 - life-science-alliance.org
During the COVID-19 pandemic, RNA-seq datasets were produced to investigate the virus–
host relationship. However, much of these data remains underexplored. To improve the …