[HTML][HTML] The role of lipid metabolism in COVID-19 virus infection and as a drug target

M Abu-Farha, TA Thanaraj, MG Qaddoumi… - International journal of …, 2020 - mdpi.com
The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million
people and resulted in the death of over one hundred thousand people at the time of writing …

[HTML][HTML] The fatty acid lipid metabolism nexus in COVID-19

JE Tanner, C Alfieri - Viruses, 2021 - mdpi.com
Enteric symptomology seen in early-stage severe acute respiratory syndrome (SARS)-2003
and COVID-19 is evidence of virus replication occurring in the intestine, liver and pancreas …

Dissecting lipid metabolism alterations in SARS-CoV-2

I Casari, M Manfredi, P Metharom, M Falasca - Progress in lipid research, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic that has infected over a hundred million people globally. There have been …

[HTML][HTML] Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19

M Caterino, M Gelzo, S Sol, R Fedele, A Annunziata… - Scientific reports, 2021 - nature.com
In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 …

Alterations of lipid profile in COVID-19: a narrative review

A Rezaei, S Neshat, K Heshmat-Ghahdarijani - Current Problems in …, 2022 - Elsevier
The COVID-19 pandemic has led to over 100 million infections and over 3 million deaths
worldwide. Understanding its pathogenesis is crucial to guide prognostic and therapeutic …

[HTML][HTML] COVID-19: direct and indirect mechanisms of statins

A Pawlos, M Niedzielski, P Gorzelak-Pabiś… - International Journal of …, 2021 - mdpi.com
The virus responsible for the current COVID-19 pandemic is severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2): a new virus with high infectivity and moderate …

Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications

E Kočar, T Režen, D Rozman - … et Biophysica Acta (BBA)-Molecular and …, 2021 - Elsevier
Cholesterol is being recognized as a molecule involved in regulating the entry of the SARS-
CoV-2 virus into the host cell. However, the data about the possible role of cholesterol …

[HTML][HTML] The roles of lipids in SARS-CoV-2 viral replication and the host immune response

KN Theken, SY Tang, S Sengupta, GA FitzGerald - Journal of lipid research, 2021 - ASBMB
The significant morbidity and mortality associated with severe acute respiratory syndrome
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …

[HTML][HTML] Characterization of the lipidomic profile of human coronavirus-infected cells: implications for lipid metabolism remodeling upon coronavirus replication

B Yan, H Chu, D Yang, KH Sze, PM Lai, S Yuan… - Viruses, 2019 - mdpi.com
Lipids play numerous indispensable cellular functions and are involved in multiple steps in
the replication cycle of viruses. Infections by human-pathogenic coronaviruses result in …

[HTML][HTML] Potential COVID-19 therapeutics from a rare disease: weaponizing lipid dysregulation to combat viral infectivity

SL Sturley, T Rajakumar, N Hammond, K Higaki… - Journal of lipid …, 2020 - ASBMB
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus (SARS-CoV)-2 has resulted in the death of more than 328,000 …