Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK

Z Iqbal, JH Ho, S Adam, M France, A Syed, D Neely… - Atherosclerosis, 2020 - Elsevier
The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) which causes Coronavirus Disease 2019 (COVID-19) has resulted in a pandemic. SARS …

[HTML][HTML] Alteration in the lipid profile and the desaturases activity in patients with severe pneumonia by SARS-CoV-2

I Pérez-Torres, V Guarner-Lans, E Soria-Castro… - Frontiers in …, 2021 - frontiersin.org
The kidnapping of the lipid metabolism of the host's cells by severe acute respiratory
syndrome (SARS-CoV-2) allows the virus to transform the cells into optimal machines for its …

[PDF][PDF] Plasma metabolomic and lipidomic alterations associated with COVID-19

D Wu, T Shu, X Yang, JX Song, M Zhang… - National Science …, 2020 - academic.oup.com
The pandemic of the coronavirus disease 2019 (COVID-19) has become a global public
health crisis. The symptoms of COVID-19 range from mild to severe, but the physiological …

[HTML][HTML] SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

DW Sanders, CC Jumper, PJ Ackerman, D Bracha… - Elife, 2021 - elifesciences.org
Many enveloped viruses induce multinucleated cells (syncytia), reflective of membrane
fusion events caused by the same machinery that underlies viral entry. These syncytia are …

[HTML][HTML] Disturbed lipid and amino acid metabolisms in COVID-19 patients

M Masoodi, M Peschka, S Schmiedel… - Journal of molecular …, 2022 - Springer
Abstract The Coronavirus disease 2019 (COVID-19) pandemic is overwhelming the
healthcare systems. Identification of systemic reactions underlying COVID-19 will lead to …

[HTML][HTML] A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants

SE Farley, JE Kyle, HC Leier, LM Bramer… - Nature …, 2022 - nature.com
A comprehensive understanding of host dependency factors for SARS-CoV-2 remains
elusive. Here, we map alterations in host lipids following SARS-CoV-2 infection using …

[HTML][HTML] The role of high-density lipoprotein in COVID-19

G Wang, J Deng, J Li, C Wu, H Dong, S Wu… - Frontiers in …, 2021 - frontiersin.org
The current Coronavirus disease 2019 (COVID-19) pandemic has become a global
challenge. Managing a large number of acutely ill patients in a short time, whilst reducing …

[HTML][HTML] Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators

SSG Dias, VC Soares, AC Ferreira… - PLoS …, 2020 - journals.plos.org
Viruses are obligate intracellular parasites that make use of the host metabolic machineries
to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus …

Low-density lipoprotein is a potential predictor of poor prognosis in patients with coronavirus disease 2019

J Fan, H Wang, G Ye, X Cao, X Xu, W Tan, Y Zhang - Metabolism, 2020 - Elsevier
Background The pandemic of coronavirus disease 2019 (COVID-19) has become a global
threat to public health. The lipid pathophysiology in COVID-19 is unknown. Methods In this …

[HTML][HTML] Plasma linoleate diols are potential biomarkers for severe COVID-19 infections

CB McReynolds, I Cortes-Puch, R Ravindran… - Frontiers in …, 2021 - frontiersin.org
Polyunsaturated fatty acids are metabolized into regulatory lipids important for initiating
inflammatory responses in the event of disease or injury and for signaling the resolution of …