The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

Identifying genes for schizophrenia through classical genetic approaches has proven
arduous. Here, we present a comprehensive convergent analysis that translationally …

Schizophrenia is a debilitating mental illness that affects 1% of the population. Despite
intensive study, its molecular etiology remains enigmatic. Like many common diseases …

Schizophrenia epidemiology can provide us with valuable information to guide research
directions. However, while epidemiology is useful for generating candidate risk factors, it can …

After two decades of frustration, genetic studies of schizophrenia have entered an era of
spectacular success. Advances in genotyping technologies and high throughput …

Schizophrenia (SZ) is a common and severe psychiatric disorder with both environmental
and genetic risk factors, and a high heritability. After over 20 years of molecular genetics …

Genome-wide association studies (GWASs) have successfully identified 145 genomic
regions that contribute to schizophrenia risk, but linkage disequilibrium makes it challenging …

Schizophrenia is a major psychiatric disorder that lacks a unifying neuropathology, while
currently available pharmacological treatments provide only limited benefits to many …

Epigenetic mechanisms are an important heritable and dynamic means of regulating various
genomic functions, including gene expression, to orchestrate brain development, adult …

Schizophrenia is a complex, devastating brain disorder with clear genetic and
environmental contributions to the emergence of the disease. In the last several decades of …