Early suppressive mechanisms and the negative blood oxygenation level-dependent response in human visual cortex

AR Wade, J Rowland - Journal of Neuroscience, 2010 - Soc Neuroscience
Functional magnetic resonance imaging (fMRI) studies of early sensory cortex often
measure stimulus-driven increases in the blood oxygenation level-dependent (BOLD) …

Negative BOLD fMRI response in the visual cortex carries precise stimulus-specific information

D Bressler, N Spotswood, D Whitney - PLoS One, 2007 - journals.plos.org
Sustained positive BOLD (blood oxygen level-dependent) activity is employed extensively in
functional magnetic resonance imaging (fMRI) studies as evidence for task or stimulus …

MRI of functional deactivation: temporal and spatial characteristics of oxygenation-sensitive responses in human visual cortex

P Fransson, G Krüger, KD Merboldt, J Frahm - Neuroimage, 1999 - Elsevier
Magnetic resonance imaging (MRI) of neuronal “activation” relies on the elevation of blood
flow and oxygenation and a related increase of the blood oxygenation level-dependent …

Sustained negative BOLD, blood flow and oxygen consumption response and its coupling to the positive response in the human brain

A Shmuel, E Yacoub, J Pfeuffer, PF Van de Moortele… - Neuron, 2002 - cell.com
Most fMRI studies are based on the detection of a positive BOLD response (PBR). Here, we
demonstrate and characterize a robust sustained negative BOLD response (NBR) in the …

Analysis of oxygen metabolism implies a neural origin for the negative BOLD response in human visual cortex

BN Pasley, BA Inglis, RD Freeman - Neuroimage, 2007 - Elsevier
The sustained negative blood oxygenation level-dependent (BOLD) response in functional
MRI is observed universally, but its interpretation is controversial. The origin of the negative …

High-resolution fMRI reveals laminar differences in neurovascular coupling between positive and negative BOLD responses

J Goense, H Merkle, NK Logothetis - Neuron, 2012 - cell.com
The six cortical layers have distinct anatomical and physiological properties, like different
energy use and different feedforward and feedback connectivity. It is not known if and how …

BOLD responses in human primary visual cortex are insensitive to substantial changes in neural activity

JB Swettenham, SD Muthukumaraswamy… - Frontiers in human …, 2013 - frontiersin.org
The relationship between blood oxygenation level dependent-functional magnetic
resonance imaging (BOLD-fMRI) and magnetoencephalography (MEG) metrics were …

Analysis of time and space invariance of BOLD responses in the rat visual system

CJ Bailey, BG Sanganahalli, P Herman… - Cerebral …, 2013 - academic.oup.com
Neuroimaging studies of functional magnetic resonance imaging (fMRI) and
electrophysiology provide the linkage between neural activity and the blood oxygenation …

Echo-time dependence of the BOLD response transients–a window into brain functional physiology

M Havlicek, D Ivanov, BA Poser, K Uludag - Neuroimage, 2017 - Elsevier
The blood oxygenation level-dependent (BOLD) fMRI response to neuronal activation
results from a complex interplay of induced metabolic and vascular changes. Thus, its …

Negative functional MRI response correlates with decreases in neuronal activity in monkey visual area V1

A Shmuel, M Augath, A Oeltermann… - Nature neuroscience, 2006 - nature.com
Most functional brain imaging studies use task-induced hemodynamic responses to infer
underlying changes in neuronal activity. In addition to increases in cerebral blood flow and …