[HTML][HTML] Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
L Vanderbeke, P Van Mol, Y Van Herck… - Nature …, 2021 - nature.com
Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced …
triggering of an aberrant host immune response, more so than on direct virus-induced …
Distinct cytokine profiles associated with COVID-19 severity and mortality
K Dorgham, P Quentric, M Gökkaya, S Marot… - Journal of Allergy and …, 2021 - Elsevier
Background Markedly elevated levels of proinflammatory cytokines and defective type-I
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19) …
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19) …
Cytokine storm induced by SARS-CoV-2
P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …
Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19
ER Mann, M Menon, SB Knight, JE Konkel… - Science …, 2020 - science.org
COVID-19 pathogenesis is associated with an exaggerated immune response. However, the
specific cellular mediators and inflammatory components driving diverse clinical disease …
specific cellular mediators and inflammatory components driving diverse clinical disease …
An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis
Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …
The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease
Severe COVID-19 associated pneumonia patients may exhibit features of systemic hyper-
inflammation designated under the umbrella term of macrophage activation syndrome …
inflammation designated under the umbrella term of macrophage activation syndrome …
[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19
JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients
Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …
Coronavirus disease 2019: investigational therapies in the prevention and treatment of hyperinflammation
I Amigues, AH Pearlman, A Patel, P Reid… - Expert review of …, 2020 - Taylor & Francis
Introduction: The mortality of coronavirus disease 2019 (COVID-19) is frequently driven by
an injurious immune response characterized by the development of acute respiratory …
an injurious immune response characterized by the development of acute respiratory …
[HTML][HTML] Cytokine storms in the course of COVID-19 and haemophagocytic lymphohistiocytosis in pregnant and postpartum women
A Obuchowska, A Standyło, K Obuchowska… - Biomolecules, 2021 - mdpi.com
The term 'cytokine storm'(CS) applies to a pathological autoimmune reaction when the
interactions that lead to cytokine production are destabilised and may even lead to death …
interactions that lead to cytokine production are destabilised and may even lead to death …