A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

WD Hill, RE Marioni, O Maghzian, SJ Ritchie… - Molecular …, 2019 - nature.com
Intelligence, or general cognitive function, is phenotypically and genetically correlated with
many traits, including a wide range of physical, and mental health variables. Education is …

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

JE Savage, PR Jansen, S Stringer, K Watanabe… - Nature …, 2018 - nature.com
Intelligence is highly heritable and a major determinant of human health and well-being.
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals

JRI Coleman, J Bryois, HA Gaspar, PR Jansen… - Molecular …, 2019 - nature.com
Variance in IQ is associated with a wide range of health outcomes, and 1% of the population
are affected by intellectual disability. Despite a century of research, the fundamental neural …

Genome-wide association studies establish that human intelligence is highly heritable and polygenic

G Davies, A Tenesa, A Payton, J Yang, SE Harris… - Molecular …, 2011 - nature.com
General intelligence is an important human quantitative trait that accounts for much of the
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …

The new genetics of intelligence

R Plomin, S Von Stumm - Nature Reviews Genetics, 2018 - nature.com
Intelligence—the ability to learn, reason and solve problems—is at the forefront of
behavioural genetic research. Intelligence is highly heritable and predicts important …

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

S Sniekers, S Stringer, K Watanabe, PR Jansen… - Nature …, 2017 - nature.com
Intelligence is associated with important economic and health-related life outcomes 1.
Despite intelligence having substantial heritability 2 (0.54) and a confirmed polygenic …

Genetic variation, brain, and intelligence differences

IJ Deary, SR Cox, WD Hill - Molecular psychiatry, 2022 - nature.com
Individual differences in human intelligence, as assessed using cognitive test scores, have a
well-replicated, hierarchical phenotypic covariance structure. They are substantially stable …

A general dimension of genetic sharing across diverse cognitive traits inferred from molecular data

J de la Fuente, G Davies, AD Grotzinger… - Nature Human …, 2021 - nature.com
It has been known since 1904 that, in humans, diverse cognitive traits are positively
intercorrelated. This forms the basis for the general factor of intelligence (g). Here, we …

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

JW Trampush, MLZ Yang, J Yu, E Knowles… - Molecular …, 2017 - nature.com
The complex nature of human cognition has resulted in cognitive genomics lagging behind
many other fields in terms of gene discovery using genome-wide association study (GWAS) …

Genetics and intelligence differences: five special findings

R Plomin, IJ Deary - Molecular psychiatry, 2015 - nature.com
Intelligence is a core construct in differential psychology and behavioural genetics, and
should be so in cognitive neuroscience. It is one of the best predictors of important life …