We report the convergent synthesis of bicyclo [3.1. 0] hexanes possessing an all-carbon
quaternary center via a (3+ 2) annulation of cyclopropenes with cyclopropylanilines. Using …

Stereoselective synthesis of a cyclopentane nucleus by convergent annulation constitutes a
significant challenge for synthetic chemists. Although a number of biologically relevant …

Tetrahydrofuran rings are common structural elements present in numerous biologically
active naturally occurring molecules, including a number of lignans and polyether …

New methods for the construction of highly substituted carbocycles with a defined
configuration are important for the synthesis of natural products and drugs.[1] The synthesis …

Bicyclo [2.1. 1] hexanes have become increasingly popular building blocks in medicinal
chemistry as bridged scaffolds that provide unexplored chemical space. We herein report a …

We report a new simple method to access highly substituted cyclopentanes via Lewis acid-
initiated formal [3+ 2]-cycloaddition of donor–acceptor cyclopropanes to 1, 3-dienes. This …

We designed a sequential three-step, one-pot reaction (homoallyl-homoallyl radical
rearrangement reaction) to generate highly functionalized bicyclo [2.2. 2] octane ring system …

The development of a general catalytic method for the direct and stereoselective
construction of cyclopropanes bearing highly congested vicinal all-carbon quaternary …

Cyclopropanes are important structural motifs found in numerous bioactive molecules, and a
number of methods are available for their synthesis. However, one of the simplest …

A novel Lewis acid catalyzed formal intramolecular [3+ 3] cross-cycloaddition (IMCC) of
cyclopropane 1, 1-diesters has been successfully developed. This supplies an efficient and …