The changes in surface energetics with relative humidity of carbamazepine and paracetamol as measured by inverse gas chromatography

MR Sunkersett, IM Grimsey, SW Doughty… - European journal of …, 2001 - Elsevier
The surface energetic parameters of carbamazepine and paracetamol have been studied
using inverse gas chromatography modified to produce dry and ambient conditions within …

Critical assessment of inverse gas chromatography as means of assessing surface free energy and acid–base interaction of pharmaceutical powders

MJ Telko, AJ Hickey - Journal of pharmaceutical sciences, 2007 - Elsevier
Inverse gas chromatography (IGC) has been employed as a research tool for decades.
Despite this record of use and proven utility in a variety of applications, the technique is not …

Investigating the applicability of inverse gas chromatography to binary powdered systems: An application of surface heterogeneity profiles to understanding …

JF Gamble, RN Davé, S Kiang, MM Leane… - International journal of …, 2013 - Elsevier
The aim of this study was to investigate the applicability of surface energy characterization
tools such as inverse gas chromatography for the analysis of binary systems. Drug …

Characterisation of the surface energetics of milled dl-propranolol hydrochloride using inverse gas chromatography and molecular modelling

P York, MD Ticehurst, JC Osborn, RJ Roberts… - International journal of …, 1998 - Elsevier
Inverse gas chromatography (IGC) has been successfully used to characterise the nature of
the surface of samples of dl-propranolol hydrochloride which have been produced under …

Prediction of drug-polymer interactions in binary mixtures using energy balance supported by inverse gas chromatography

T Školáková, L Souchová, J Patera, M Pultar… - European Journal of …, 2019 - Elsevier
Surface energy is extensively adopted to predict the surface properties of materials
nowadays. Our study was aimed at utilizing the surface free energy measured by inverse …

Surface energy analysis as a tool to probe the surface energy characteristics of micronized materials—A comparison with inverse gas chromatography

JF Gamble, M Leane, D Olusanmi, M Tobyn… - International journal of …, 2012 - Elsevier
This study investigates the impact of micronization on the measured surface energy
characteristics of an active pharmaceutical ingredient (API), Ibipinabant, by inverse gas …

The use of inverse phase gas chromatography to study the glass transition temperature of a powder surface

G Buckton, A Ambarkhane, K Pincott - Pharmaceutical research, 2004 - Springer
Purpose. To measure the glass transition temperature (Tg) at the surface of a hydrophobic
particle at different temperatures and humidities, on the hypothesis that the surface may be …

A comparison of two contact angle measurement methods and inverse gas chromatography to assess the surface energies of theophylline and caffeine

JW Dove, G Buckton, C Doherty - International journal of pharmaceutics, 1996 - Elsevier
The wettability of two powders has been assessed by three methods and values for surface
energies have been determined. Two contact angle methods have been used, both of which …

The importance of surface energetics of powders for drug delivery and the establishment of inverse gas chromatography

G Buckton, H Gill - Advanced drug delivery reviews, 2007 - Elsevier
Powders are complex systems with more than one value for surface energy. The presence of
different faces, defects, physical forms and impurities will alter the surface properties. There …

Isothermal microcalorimetry and inverse phase gas chromatography to study small changes in powder surface properties

G Buckton, JW Dove, P Davies - International journal of pharmaceutics, 1999 - Elsevier
It is known that processing can alter the surface energetics of powders. In this study a
sample of drug has been processed by use of different drying techniques. The samples were …