IL-1 is a polypeptide product of various cells that mediates several components of the acute-
phase response to infection and injury. Its most dramatic biological property is its ability to …

Abstract Background: Interleukin 1 (IL-1) is a key mediator of bowel inflammation, but there
is limited knowledge about the amount and site of production of this cytokine in the …

Pretreatment with low-dose IL-1 has protective effects in animal models of inflammation or
tissue injury, but the mechanisms of these protective effects are not established. To …

Interleukin 1 is a polypeptide cytokine produced by various cell types and has been shown
to have a major role in inflammatory and immunological responses. In experimental colitis it …

Abstract Local interleukin-6 (IL-6) activity was studied using colonic mucosal tissues in
inflammatory bowel disease (IBD) and inflammatory control patients. Active IBD specimens …

Interleukin 1 (IL-1) may be a key mediator of inflammation and tissue damage in
inflammatory bowel disease (IBD). In rabbits with immune complex-induced colitis, IL-1 …

BACKGROUND & AIMS: Interleukin (IL) 4 has immunoregulatory and anti-inflammatory
activities, but little is known about IL-4 in the human gut. We investigated production of IL-4 …

Interleukin-6, a cytokine produced by various cell types, has a major role in inflammatory
and immunological reactions. To define its potential role in inflammatory bowel disease, its …

The effects of human recombinant interleukin-1 receptor antagonist (IL-1ra) on inflammation,
tissue damage, and production of inflammatory mediators in rabbit formalin-immune …

Abstract Interleukin-1 (IL-1) represents a family of polypeptides with a wide range of
biological activities. At least two dissimilar gene products have been cloned; there are …