Impact of initial antibiotic choice on mortality from pneumococcal pneumonia

J Aspa, O Rajas, FR de Castro… - European …, 2006 - Eur Respiratory Soc
To determine the impact of initial antimicrobial choice on 30-day mortality rate in patients
with community-acquired pneumonia due to Streptococcus pneumoniae (CAP-SP), a …

Addition of a macrolide to a β-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal …

JA Martínez, JP Horcajada, M Almela… - Clinical Infectious …, 2003 - academic.oup.com
To assess the association between inclusion of a macrolide in a β-lactam—based empirical
antibiotic regimen and mortality among patients with bacteremic pneumococcal pneumonia …

Determinants of outcome in patients with bacteraemic pneumococcal pneumonia: importance of early adequate treatment

J Garnacho-Montero, E Garcia-Cabrera… - … journal of infectious …, 2010 - Taylor & Francis
We set out to determine the factors influencing mortality in 125 adult patients with
bacteraemic pneumococcal community-acquired pneumonia (CAP), assessing the impact …

Decrease in mortality in severe community-acquired pneumococcal pneumonia: impact of improving antibiotic strategies (2000-2013)

S Gattarello, B Borgatta, J Solé-Violán, J Vallés… - Chest, 2014 - Elsevier
OBJECTIVE The objective of the present study was to compare antibiotic prescribing
practices and survival in the ICU for patients with pneumococcal severe community-acquired …

Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumonia

P Naucler, J Darenberg, E Morfeldt, Å Örtqvist… - Thorax, 2013 - thorax.bmj.com
Rationale Host and bacterial factors as well as different treatment regimens are likely to
influence the outcome in patients with bacteraemic pneumococcal pneumonia. Objectives …

Impact of antibiotic de-escalation on clinical outcomes in community-acquired pneumococcal pneumonia

D Viasus, AF Simonetti, C Garcia-Vidal… - Journal of …, 2017 - academic.oup.com
Background Although antibiotic de-escalation is regarded as a measure that reduces
selection pressure, adverse drug effects and costs, evidence supporting this practice in …

Clinical outcomes of bacteremic pneumococcal pneumonia in the era of antibiotic resistance

JF Moroney, AE Fiore, LH Harrison… - Clinical Infectious …, 2001 - academic.oup.com
Limited data are available about the impact of antimicrobial resistance on clinical outcomes
in cases of pneumococcal pneumonia. This was studied in 146 persons hospitalized with …

Optimal therapy for severe pneumococcal community-acquired pneumonia

M Luján, M Gallego, J Rello - Intensive care medicine, 2006 - Springer
Streptococcus pneumoniae is responsible for two-thirds of ICU admissions due to
community-acquired pneumonia (CAP) and is the leading cause of CAP-related death. Early …

Severity scoring in community-acquired pneumonia caused by Streptococcus pneumoniae: a 5-year experience

OC Ioachimescu, AG Ioachimescu, PB Iannini - International journal of …, 2004 - Elsevier
Multiple severity scoring systems have been devised and evaluated in community-acquired
pneumonia (CAP), but a simplified set of prognostic indicators has not yet been developed …

Sepsis severity predicts outcome in community-acquired pneumococcal pneumonia

B Schaaf, J Kruse, J Rupp, RR Reinert… - European …, 2007 - Eur Respiratory Soc
Easily performed prognostic rules are helpful for guiding the intensity of monitoring and
treatment of patients. The aim of the present study was to compare the predictive value of the …