Context.—Serious noninfectious complications are far more likely to occur than viral disease
transmission from blood component transfusion. Objective.—To compile a comprehensive …

Each year, more than 4 million patients receive a blood transfusion in the United States to
control symptoms associated with anemia, coagulopathy, thrombocytopenia, or some …

As infectious complications from blood transfusion have decreased because of improved
donor questionnaires and sophisticated infectious disease blood screening, noninfectious …

The article discusses the success that has been achieved by application of novel
approaches and findings from other fields to study transfusion complications. Insights from …

Blood transfusion is considered safe when the infused blood is tested using state of the art
viral assays developed over the past several decades. Only rarely are known viruses like …

The benefits of blood transfusion must be considered and evaluated in terms of risk factors
relating to the adverse effects of transfusion. Transfusions may result in either serious or …

Over the past decades, the incidence of clinically significant transfusion‐transmitted
diseases has been dramatically reduced. These reductions have occurred because of a …

BACKGROUND: Bacterial contamination of blood components can result in transfusion‐
transmitted infection, but the risk is not established. STUDY DESIGN AND METHODS …

As a result of significant progress in reducing the risks of transfusion-transmitted viral
infections, bacterial contamination of platelet components (1: 2,000) and sepsis (1: 50,000) …

Serious adverse effects of transfusion may be immunologically or non-immunologically
mediated. Currently, bacterial contamination of blood products, particularly platelets, is one …