Is COVID-19 an endothelial disease? Clinical and basic evidence

C Sardu, J Gambardella, MB Morelli, X Wang… - 2020 - preprints.org
The symptoms most commonly reported by patients affected by coronavirus disease 2019
(COVID-19) include cough, fever, and shortness of breath. However, other major events …

Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence

C Sardu, J Gambardella, MB Morelli, X Wang… - Journal of clinical …, 2020 - mdpi.com
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …

Is the endothelium the missing link in the pathophysiology and treatment of COVID-19 complications?

P Castro, M Palomo, AB Moreno-Castaño… - … drugs and therapy, 2022 - Springer
Patients with COVID-19 present a wide spectrum of disease severity, from asymptomatic
cases in the majority to serious disease leading to critical care and even death. Clinically …

Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19

I Bernard, D Limonta, LK Mahal, TC Hobman - Viruses, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

The endothelium as Achilles' heel in COVID-19 patients

MM Gladka, C Maack - Cardiovascular research, 2020 - academic.oup.com
The COVID-19 pandemic undoubtedly influenced the focus of many scientific fields,
including cardiovascular research, and is still a global challenge for healthcare systems. The …

The endothelium and COVID-19: an increasingly clear link brief title: endotheliopathy in COVID-19

I Six, N Guillaume, V Jacob, R Mentaverri… - International Journal of …, 2022 - mdpi.com
The endothelium has a fundamental role in the cardiovascular complications of coronavirus
disease 2019 (COVID-19). Infection with severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications

Z Ma, KY Yang, Y Huang, KO Lui - Journal of Molecular and Cellular …, 2022 - Elsevier
The global propagation of SARS-CoV-2 leads to an unprecedented public health
emergency. Despite that the lungs are the primary organ targeted by COVID-19, systemic …

COVID-19 is, in the end, an endothelial disease

P Libby, T Lüscher - European heart journal, 2020 - academic.oup.com
The vascular endothelium provides the crucial interface between the blood compartment
and tissues, and displays a series of remarkable properties that normally maintain …

Role of endothelium in cardiovascular sequelae of long COVID

L Santoro, V Zaccone, L Falsetti, V Ruggieri, M Danese… - Biomedicines, 2023 - mdpi.com
The global action against coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2
infection, shed light on endothelial dysfunction. Although SARS-CoV-2 primarily affects the …

The role of endothelium in COVID-19

M Ionescu, AP Stoian, M Rizzo, D Serban… - International journal of …, 2021 - mdpi.com
The 2019 novel coronavirus, known as severe acute respiratory syndrome-coronavirus 2
(SARS-CoV-2) or coronavirus disease 2019 (COVID-19), is causing a global pandemic. The …