The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis

H Liang, C Xu, Z Pan, Y Zhang, Z Xu, Y Chen, T Li… - Molecular Therapy, 2014 - cell.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and high-lethality fibrotic lung
disease characterized by excessive fibroblast proliferation, extracellular matrix …

The anti-fibrotic effects of microRNA-153 by targeting TGFBR-2 in pulmonary fibrosis

C Liang, X Li, L Zhang, D Cui, X Quan… - … and Molecular Pathology, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial fibrotic lung disease with an
undefined etiology and no effective treatments. By binding to cell surface receptors …

The anti-fibrotic effects and mechanisms of microRNA-486-5p in pulmonary fibrosis

X Ji, B Wu, J Fan, R Han, C Luo, T Wang, J Yang… - Scientific reports, 2015 - nature.com
To identify microRNAs (miRNAs, miRs) with potential roles in lung fibrogenesis, we
performed genome-wide profiling of miRNA expression in lung tissues from a silica-induced …

Integrated analyses identify the involvement of microRNA-26a in epithelial–mesenchymal transition during idiopathic pulmonary fibrosis

H Liang, Y Gu, T Li, Y Zhang, L Huangfu, M Hu… - Cell death & …, 2014 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and highly lethal
fibrotic lung disease with poor treatment and unknown etiology. Emerging evidence …

MicroRNA-326 regulates profibrotic functions of transforming growth factor-β in pulmonary fibrosis

S Das, M Kumar, V Negi, B Pattnaik… - American journal of …, 2014 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a fatal disorder resulting from the progressive
remodeling of lungs, with no known effective treatment. Although transforming growth factor …

miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway

X Zeng, C Huang, L Senavirathna, P Wang, L Liu - BMC cell biology, 2017 - Springer
Background MicroRNAs are a group of small RNAs that regulate gene expression at the
posttranscriptional level. They regulate almost every aspect of cellular processes. In this …

MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation

C Huang, X Xiao, Y Yang, A Mishra, Y Liang… - Journal of Biological …, 2017 - ASBMB
Aberrant proliferation and activation of lung fibroblasts contribute to the initiation and
progression of idiopathic pulmonary fibrosis (IPF). However, the mechanisms responsible for …

MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation

H Cui, S Banerjee, N Xie, J Ge, RM Liu… - American journal of …, 2016 - atsjournals.org
Although microRNAs (miRs) have been well recognized to play an important role in the
pathogenesis of organ fibrosis, there is a lack of evidence as to whether miRs directly …

MicroRNAs in idiopathic pulmonary fibrosis

KV Pandit, J Milosevic, N Kaminski - Translational research, 2011 - Elsevier
In this review, we describe the recent advances in the understanding of the role of
microRNAs in idiopathic pulmonary fibrosis (IPF), a chronic progressive and lethal fibrotic …

miR-29 inhibits bleomycin-induced pulmonary fibrosis in mice

J Xiao, XM Meng, XR Huang, ACK Chung, YL Feng… - Molecular Therapy, 2012 - cell.com
Loss of microRNA-29 (miR-29) is known to be a mechanism of transforming growth factor-β
(TGF-β)-mediated pulmonary fibrosis, but the therapeutic implication of miR-29 for …