Prevention of human cancer by modulation of chronic inflammatory processes

H Ohshima, H Tazawa, BS Sylla, T Sawa - Mutation Research/Fundamental …, 2005 - Elsevier
Chronic inflammation induced by biological, chemical and physical factors has been
associated with increased risk of human cancer at various sites. Inflammation facilitates the …

Identifying and defusing weapons of mass inflammation in carcinogenesis

LJ Hofseth, L Ying - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2006 - Elsevier
The continued cancer risks associated with chronic inflammation necessitate the
identification of inflammatory molecules and the cancer pathways they affect. Evidence …

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

MK Shanmugam, JH Lee, EZP Chai, MM Kanchi… - Seminars in cancer …, 2016 - Elsevier
The association between chronic inflammation and cancer development has been well
documented. One of the major obstacles in cancer treatment is the persistent autocrine and …

Genetic aspects of inflammation and cancer

GL Hold, ME El-Omar - Biochemical Journal, 2008 - portlandpress.com
Chronic inflammation is involved in the pathogenesis of most common cancers. The
aetiology of the inflammation is varied and includes microbial, chemical and physical …

Chronic inflammation and oxidative stress in human carcinogenesis

A Federico, F Morgillo, C Tuccillo… - … journal of cancer, 2007 - Wiley Online Library
A wide array of chronic inflammatory conditions predispose susceptible cells to neoplastic
transformation. In general, the longer the inflammation persists, the higher the risk of cancer …

Chemical basis of inflammation-induced carcinogenesis

H Ohshima, M Tatemichi, T Sawa - Archives of biochemistry and biophysics, 2003 - Elsevier
Chronic inflammation induced by biological, chemical, and physical factors has been
associated with increased risk of human cancer at various sites. Inflammation activates a …

Inflammation, a key event in cancer development

H Lu, W Ouyang, C Huang - Molecular cancer research, 2006 - AACR
Several recent studies have identified nuclear factor-κB as a key modulator in driving
inflammation to cancers. Besides this transcription factor, essential in regulating …

Molecular pathways in cancer-related inflammation

A Dep Prete, P Allavena, G Santoro, R Fumarulo… - Biochemia …, 2011 - hrcak.srce.hr
Sažetak Accumulating evidence shows that chronic inflammation is associated to increased
risk of cancer. An inflammatory component is present also in the microenvironment of …

Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe

BB Aggarwal, RV Vijayalekshmi, B Sung - Clinical cancer research, 2009 - AACR
Chronic infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and high-
calorie diet have been recognized as major risk factors for the most common types of cancer …

Chronic inflammation: a common and important factor in the pathogenesis of neoplasia

D Schottenfeld, J Beebe‐Dimmer - CA: a cancer journal for …, 2006 - Wiley Online Library
A causal link between chronic inflammation and carcinogenesis is explored by reviewing
illustrative examples of specific cancers and causal agents and mechanisms. The causal …