[HTML][HTML] Statistical and machine learning methods for spatially resolved transcriptomics with histology

J Hu, A Schroeder, K Coleman, C Chen… - Computational and …, 2021 - Elsevier
Recent developments in spatially resolved transcriptomics (SRT) technologies have
enabled scientists to get an integrated understanding of cells in their morphological context …

ASAP: a web-based platform for the analysis and interactive visualization of single-cell RNA-seq data

V Gardeux, FPA David, A Shajkofci, PC Schwalie… - …, 2017 - academic.oup.com
Motivation Single-cell RNA-sequencing (scRNA-seq) allows whole transcriptome profiling of
thousands of individual cells, enabling the molecular exploration of tissues at the cellular …

Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data

J Tanevski, T Nguyen, B Truong… - Life Science …, 2020 - life-science-alliance.org
Single-cell RNA-sequencing (scRNAseq) technologies are rapidly evolving. Although very
informative, in standard scRNAseq experiments, the spatial organization of the cells in the …

Splotch: robust estimation of aligned spatial temporal gene expression data

T Äijö, S Maniatis, S Vickovic, K Kang, M Cuevas… - bioRxiv, 2019 - biorxiv.org
Spatial genomics technologies enable new approaches to study how cells interact and
function in intact multicellular environments but present a host of technical and …

SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes

M Elosua-Bayes, P Nieto, E Mereu, I Gut… - Nucleic acids …, 2021 - academic.oup.com
Spatially resolved gene expression profiles are key to understand tissue organization and
function. However, spatial transcriptomics (ST) profiling techniques lack single-cell …

ST Pipeline: an automated pipeline for spatial mapping of unique transcripts

JF Navarro, J Sjöstrand, F Salmén, J Lundeberg… - …, 2017 - academic.oup.com
Motivation In recent years we have witnessed an increase in novel RNA-seq based
techniques for transcriptomics analysis. Spatial transcriptomics is a novel RNA-seq based …

STOmicsDB: a database of spatial transcriptomic data

Z Xu, W Wang, T Yang, J Chen, Y Huang, J Gould… - bioRxiv, 2022 - biorxiv.org
Recent technological development in spatial transcriptomics allows researchers to measure
gene expression of cells and their spatial locations at the almost single-cell level, which …

Spatial mapping of cell types by integration of transcriptomics data

A Andersson, J Bergenstråhle, M Asp, L Bergenstråhle… - bioRxiv, 2019 - biorxiv.org
Spatial transcriptomics and single cell RNA-sequencing offer complementary insights into
the transcriptional expression landscape. We here present a probabilistic method that …

Identifying spatial co-occurrence in healthy and inflamed tissues (ISCHIA)

A Lafzi, C Borrelli, S Baghai Sain, K Bach… - Molecular Systems …, 2024 - embopress.org
Sequencing-based spatial transcriptomics (ST) methods allow unbiased capturing of RNA
molecules at barcoded spots, charting the distribution and localization of cell types and …

Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace

J Qian, J Liao, Z Liu, Y Chi, Y Fang, Y Zheng… - Nature …, 2023 - nature.com
Tissues are highly complicated with spatial heterogeneity in gene expression. However, the
cutting-edge single-cell RNA-seq technology eliminates the spatial information of individual …