[HTML][HTML] Encoding method of single-cell spatial transcriptomics sequencing

Y Zhou, E Jia, M Pan, X Zhao, Q Ge - International journal of …, 2020 - ncbi.nlm.nih.gov
Despite significant advances in parallel single-cell RNA sequencing revealing astonishing
cellular heterogeneity in many tissue types, the spatial information in the tissue context …

Principles of spatial transcriptomics analysis: a practical walk-through in kidney tissue

T Noel, QS Wang, A Greka, JL Marshall - Frontiers in Physiology, 2022 - frontiersin.org
Spatial transcriptomic technologies capture genome-wide readouts across biological tissue
space. Moreover, recent advances in this technology, including Slide-seqV2, have achieved …

Characterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomic data with nonuniform cellular densities

BF Miller, D Bambah-Mukku, C Dulac… - Genome …, 2021 - genome.cshlp.org
Recent technological advances have enabled spatially resolved measurements of
expression profiles for hundreds to thousands of genes in fixed tissues at single-cell …

Cell composition inference and identification of layer-specific spatial transcriptional profiles with POLARIS

J Chen, T Luo, M Jiang, J Liu, GP Gupta, Y Li - Science Advances, 2023 - science.org
Spatial transcriptomics (ST) technology, providing spatially resolved transcriptional profiles,
facilitates advanced understanding of key biological processes related to health and …

Bento: a toolkit for subcellular analysis of spatial transcriptomics data

CK Mah, N Ahmed, NA Lopez, DC Lam, A Pong… - Genome Biology, 2024 - Springer
The spatial organization of molecules in a cell is essential for their functions. While current
methods focus on discerning tissue architecture, cell–cell interactions, and spatial …

Spatial-ATAC-seq: spatially resolved chromatin accessibility profiling of tissues at genome scale and cellular level

Y Deng, M Bartosovic, S Ma, D Zhang, Y Liu, X Qin… - bioRxiv, 2021 - biorxiv.org
Cellular function in tissue is dependent upon the local environment, requiring new methods
for spatial mapping of biomolecules and cells in the tissue context. The emergence of spatial …

WebAtlas pipeline for integrated single cell and spatial transcriptomic data

T Li, D Horsfall, D Basurto-Lozada, K Roberts, M Prete… - bioRxiv, 2023 - biorxiv.org
Single cell and spatial transcriptomics illuminate complementary features of tissues.
However, online dissemination and exploration of integrated datasets is challenging due to …

Robust decomposition of cell type mixtures in spatial transcriptomics

DM Cable, E Murray, LS Zou, A Goeva… - Nature …, 2022 - nature.com
A limitation of spatial transcriptomics technologies is that individual measurements may
contain contributions from multiple cells, hindering the discovery of cell-type-specific spatial …

scmap-A tool for unsupervised projection of single cell RNA-seq data

VY Kiselev, A Yiu, M Hemberg - BioRxiv, 2017 - biorxiv.org
Single-cell RNA-seq (scRNA-seq) is widely used to investigate the composition of complex
tissues–since the technology allows researchers to define cell-types using unsupervised …

ScRNA-seq and ST-seq in liver research

J He, C Deng, L Krall, Z Shan - Cell Regeneration, 2023 - Springer
Spatial transcriptomics, which combine gene expression data with spatial information, has
quickly expanded in recent years. With application of this method in liver research, our …