Background—We evaluated whether angiotensin II (Ang II) influenced intercellular adhesion
molecule (ICAM)-1 expression by human vascular endothelial cells derived from umbilical …

Intercellular adhesion molecule-1 (ICAM-1), part of an immunoglobulin-like superfamily of
adhesion molecules, is involved in several cardiovascular diseases. We investigated …

Monocyte and adhesion infiltration into the arterial subendothelium are initial steps in
hypertension development. The endothelial intercellular adhesion molecule-1 (ICAM-1) has …

Microvascular changes in the brain are significant causes of cerebral edema and ischemia
injury. A number of studies suggest that angiotensin (Ang) II may be involved in the initiation …

Clinical data suggest a link between the activation of the renin-angiotensin system and
cardiovascular ischemic events. Leukocyte accumulation in the vessel wall is a hallmark of …

Background—Cardiovascular ischemic events may occur more frequently in hypertensive
patients with activated renin-angiotensin systems. We tested the hypothesis that angiotensin …

Although leukocytes adhere in arteries in various vascular diseases, to date no endogenous
proinflammatory molecule has been identified to initiate leukocyte adhesion in the arterial …

Leukocyte recruitment is a crucial step in inflammation. Inflammatory stimuli upregulate the
expression of some endothelial adhesion molecules, such as E-selectin or ICAM-1, but not …

Angiotensin II (AII) is recognized as being an important factor in the pathogenesis of
hypertension and atherosclerosis. Monocyte binding to affected endothelial cells is one of …

THE ENDOTHELIUM IS A semipermeable barrier that regulates the exchange between
blood and peripheral tissues. The regulation of vascular permeability is an essential and …