Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
Many anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) neutralizing
antibodies target the angiotensin-converting enzyme 2 (ACE2) binding site on viral spike …
antibodies target the angiotensin-converting enzyme 2 (ACE2) binding site on viral spike …
A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site
T Onodera, S Kita, Y Adachi, S Moriyama, A Sato… - Immunity, 2021 - cell.com
Potent neutralizing SARS-CoV-2 antibodies often target the spike protein receptor-binding
site (RBS), but the variability of RBS epitopes hampers broad neutralization of multiple …
site (RBS), but the variability of RBS epitopes hampers broad neutralization of multiple …
Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses
Y Wang, M Liu, Y Shen, Y Ma, X Li, Y Zhang, M Liu… - Cell discovery, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
of concern, including Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2) …
of concern, including Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2) …
Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease …
of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease …
[HTML][HTML] Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability
Viral mutations are an emerging concern in reducing SARS-CoV-2 vaccination efficacy.
Second-generation vaccines will need to elicit neutralizing antibodies against sites that are …
Second-generation vaccines will need to elicit neutralizing antibodies against sites that are …
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice
Severe acute respiratory syndrome coronaviruses 1 (SARS-CoV) and 2 (SARS-CoV-2),
including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality …
including SARS-CoV-2 variants of concern, can cause deadly infections. The mortality …
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
The emergence of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into …
variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into …
Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages have
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
Structural and functional analysis of a potent sarbecovirus neutralizing antibody
SARS-CoV-2 is a newly emerged coronavirus responsible for the current COVID-19
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
pandemic that has resulted in more than one million infections and 73,000 deaths,. Vaccine …
Broad sarbecovirus neutralization by a human monoclonal antibody
MA Tortorici, N Czudnochowski, TN Starr, R Marzi… - Nature, 2021 - nature.com
The recent emergence of SARS-CoV-2 variants of concern,,,,,,,,–and the recurrent spillovers
of coronaviruses, into the human population highlight the need for broadly neutralizing …
of coronaviruses, into the human population highlight the need for broadly neutralizing …