The coronavirus disease 2019 (COVID-19) pandemic, caused by infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is having a deleterious impact on …
MA O'Connor, DW Hawman, K Meade-White… - Plos …, 2023 - journals.plos.org
The global SARS-CoV-2 pandemic prompted rapid development of COVID-19 vaccines. Although several vaccines have received emergency approval through various public health …
The spread of the SARS-CoV-2 into a global pandemic within a few months of onset motivates the development of a rapidly scalable vaccine. Here, we present a self-amplifying …
NN Zhang, XF Li, YQ Deng, H Zhao, YJ Huang, G Yang… - Cell, 2020 - cell.com
There is an urgent need for vaccines against coronavirus disease 2019 (COVID-19) because of the ongoing SARS-CoV-2 pandemic. Among all approaches, a messenger RNA …
The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic necessitates the fast development of vaccines to meet a worldwide need. mRNA-based …
The spread of the SARS-CoV-2 into a global pandemic within a few months of onset motivates the development of a rapidly scalable vaccine. Here, we present a self-amplifying …
DW Hawman, K Meade-White, J Archer, SS Leventhal… - Elife, 2022 - elifesciences.org
Despite mass public health efforts, the SARS-CoV2 pandemic continues as of late 2021 with resurgent case numbers in many parts of the world. The emergence of SARS-CoV2 variants …
S Rauch, N Roth, K Schwendt, M Fotin-Mleczek… - npj Vaccines, 2021 - nature.com
Abstract mRNA technologies have recently proven clinical efficacy against coronavirus disease 2019 and are among the most promising technologies to address the current …
G Maruggi, CP Mallett, JW Westerbeck, T Chen… - Molecular Therapy, 2022 - cell.com
RNA vaccines have demonstrated efficacy against SARS-CoV-2 in humans, and the technology is being leveraged for rapid emergency response. In this report, we assessed …