Biomarker research of psychiatric disorders is delayed by symptom pattern-related
diagnostic categories that are only distantly associated with biological mechanisms. In …

Substantial clinical heterogeneity and comorbidity inherent amongst mental disorders limit
the identification of neuroimaging biomarkers that can reliably track clinical symptoms …

Psychiatric diseases are very heterogeneous both in clinical manifestation and etiology.
With the recent rise of using machine learning techniques to attempt to diagnose and …

In advancing precision psychiatry, we focus on what imaging technology and computational
approaches offer for the future of diagnostic subtyping and personalized tailoring of …

Mood disorders are a highly prevalent group of mental disorders causing substantial
socioeconomic burden. There are various methodological approaches for identifying the …

Increasing sharing initiatives on neuroimaging data have provided unprecedented
opportunities to study brain disorders. Standardized approaches for capturing reproducible …

Background A major research finding in the field of Biological Psychiatry is that symptom-
based categories of mental disorders map poorly onto dysfunctions in brain circuits or …

Psychiatry continues to suffer from challenges to diagnostic validity due to lack of biological
markers. Distinctions between diagnostic categories are still largely informed on symptom …

Psychiatric research is often confronted with complex abstractions and dynamics that are not
readily accessible or well-defined to our perception and measurements, making data-driven …

Computational psychiatry is a rapidly emerging field that uses model-based quantities to
infer the behavioral and neuronal abnormalities that underlie psychopathology. If successful …