Stimuli‐Sensitive Nanotherapies for the Treatment of Osteoarthritis

Z Wang, S Wang, K Wang, X Wu… - Macromolecular …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a common chronic inflammatory disease in the joints. It is one of the
leading causes of disability with increasing morbidity, which has become one of the serious …

Combining nanotechnology with monoclonal antibody drugs for rheumatoid arthritis treatments

XK Chi, XL Xu, BY Chen, J Su, YZ Du - Journal of Nanobiotechnology, 2023 - Springer
Rheumatoid arthritis (RA) is a systemic immune disease characterized by synovial
inflammation. Patients with RA commonly experience significant damage to their hand and …

Nanomedicines for chronic non-infectious arthritis: the clinician's perspective

I Rubinstein, GL Weinberg - Nanomedicine: Nanotechnology, Biology and …, 2012 - Elsevier
Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic health conditions.
However, despite recent advances in medical therapeutics, their treatment still represents an …

Nanomedicine Strategies for Anti‐Inflammatory Treatment of Noninfectious Arthritis

L Chen, Y Wang, L Sun, J Yan… - Advanced Healthcare …, 2021 - Wiley Online Library
Noninfectious arthritis (NIA) comprises a class of chronic and progressive inflammatory
disorders that require early‐stage management to prevent disease progression. The most …

Nanocrystal–polymer particles: extended delivery carriers for osteoarthritis treatment

P Maudens, CA Seemayer, C Thauvin, C Gabay… - Small, 2018 - Wiley Online Library
An efficient treatment for osteoarthritis (OA) can benefit from the local release of a high
therapeutic dose over an extended period of time. Such a treatment will minimize systemic …

Nucleic acid nanomaterials-based therapy for osteoarthritis: Progress and prospects

Y Yao, M Yang, S Shi - Current Drug Metabolism, 2023 - ingentaconnect.com
Osteoarthritis (OA) involves lesions of the entire joint and remains one of the health
problems plaguing the world. The pathological mechanism of OA is complex and involves …

An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications

W Liang, C Zhou, S Jin, L Fu, H Zhang, X Huang… - Drug Delivery, 2023 - Taylor & Francis
Nanotechnology has made significant progress in various fields, including medicine, in
recent times. The application of nanotechnology in drug delivery has sparked a lot of …

Nanomedicine–advantages for their use in rheumatoid arthritis theranostics

S Xiao, Y Tang, Z Lv, Y Lin, L Chen - Journal of controlled release, 2019 - Elsevier
Rheumatoid arthritis (RA) is an autoimmune disease accompanies with synovial
inflammation and progressive bone destruction. Currently, anti-rheumatic drugs need high …

Nanotechnology and osteoarthritis. Part 1: clinical landscape and opportunities for advanced diagnostics

TB Lawson, JTA Mäkelä, T Klein… - Journal of …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a disease of the entire joint, often triggered by cartilage injury,
mediated by a cascade of inflammatory pathways involving a complex interplay among …

Knee osteoarthritis therapy: recent advances in intra-articular drug delivery systems

L Ma, X Zheng, R Lin, ARJ Sun, J Song… - Drug design …, 2023 - Taylor & Francis
Drug delivery for osteoarthritis (OA) treatment is a continuous challenge because of their
poor bioavailability and rapid clearance in joints. Intra-articular (IA) drug delivery is a …