Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: evolution of lesion volume and correlation with clinical outcome

C Beaulieu, A De Crespigny, DC Tong… - Annals of Neurology …, 1999 - Wiley Online Library
A prospective longitudinal diffusion‐weighted and perfusion‐weighted magnetic resonance
imaging (DWI/PWI) study of stroke patients (n= 21) at five distinct time points was performed …

Ischemic lesion volumes in acute stroke by diffusion‐weighted magnetic resonance imaging correlate with clinical outcome

KO Löuvbld, AE Baird, G Schlaug… - Annals of Neurology …, 1997 - Wiley Online Library
Diffusion‐weighted magnetic resonance imaging detects ischemic injury within minutes after
onset, and has been used to demonstrate drug efficacy in animal models of stroke. In 50 …

Diffusion‐and perfusion‐weighted MRI response to thrombolysis in stroke

MW Parsons, PA Barber, J Chalk… - Annals of Neurology …, 2002 - Wiley Online Library
Diffusion‐and perfusion‐weighted magnetic resonance imaging provides important
pathophysiological information in acute brain ischemia. We performed a prospective study in …

Time course of lesion development in patients with acute stroke: serial diffusion-and hemodynamic-weighted magnetic resonance imaging

LH Schwamm, WJ Koroshetz, AG Sorensen, B Wang… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—We sought to characterize the evolution of acute ischemic stroke
by MRI and its relationship to patients' neurological outcome. Methods—Fourteen patients …

Enlargement of human cerebral ischemic lesion volumes measured by diffusion‐weighted magnetic resonance imaging

AE Baird, A Benfield, G Schlaug… - Annals of Neurology …, 1997 - Wiley Online Library
We aimed to determine the frequency and time course of the enlargement of ischemic
cerebral lesions following human stroke and to study the effect of the state of perfusion on …

Correlation of perfusion-and diffusion-weighted MRI with NIHSS score in acute (< 6.5 hour) ischemic stroke

DC Tong, MA Yenari, GW Albers, M O'brien, MP Marks… - Neurology, 1998 - AAN Enterprises
Background: Diffusion-weighted (DWI) and perfusion-weighted (PWI) MRI are powerful new
techniques for the assessment of acute cerebral ischemia. However, quantitative data …

Clinical correlations of diffusion and perfusion lesion volumes in acute ischemic stroke

AE Baird, KO Lövblad, JF Dashe, A Connor… - Cerebrovascular …, 2000 - karger.com
The aim of this study was to describe the clinico-radiological correlations of magnetic
resonance (MR) perfusion and diffusion-weighted imaging (DWI) abnormalities in ischemic …

Clinical utility of diffusion‐weighted magnetic resonance imaging in the assessment of ischemic stroke

HL Lutsep, GW Albers, A DeCrespigny… - Annals of Neurology …, 1997 - Wiley Online Library
Diffusion‐weighted imaging (DWI) detects small changes in water diffusion that occur in
ischemic brain. This study evaluated the clinical usefulness of a phase‐navigated spin‐echo …

Characterizing the diffusion/perfusion mismatch in experimental focal cerebral ischemia

X Meng, M Fisher, Q Shen, CH Sotak… - Annals of Neurology …, 2004 - Wiley Online Library
Diffusion‐weighted imaging (DWI) and perfusion‐weighted imaging (PWI) can rapidly detect
lesions in acute ischemic stroke patients. The PWI volume is typically substantially larger …

Do acute diffusion-and perfusion-weighted MRI lesions identify final infarct volume in ischemic stroke?

CS Rivers, JM Wardlaw, PA Armitage, ME Bastin… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—An acute mismatch on diffusion-weighted MRI (DWI) and
perfusion-weighted MRI (PWI) may represent the “tissue-at-risk.” It is unclear which …