[HTML][HTML] CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular Cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

[HTML][HTML] CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

[HTML][HTML] CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7

K Zeng, X Chen, MU Xu, X Liu, X Hu, T Xu, H Sun… - Cell death & …, 2018 - nature.com
Mounting evidences indicate that circular RNAs (circRNAs) have a vital role in human
diseases, especially cancers. More recently, circHIPK3, a particularly abundant circRNA …

[HTML][HTML] CircRNA_0000392 promotes colorectal cancer progression through the miR-193a-5p/PIK3R3/AKT axis

H Xu, Y Liu, P Cheng, C Wang, Y Liu, W Zhou… - Journal of Experimental …, 2020 - Springer
Abstract Background Circular RNAs (circRNAs), important members of the noncoding RNA
family, have been recently revealed to play a role in the pathogenic progression of diseases …

Hsa_circRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway

M Wu, C Kong, M Cai, W Huang, Y Chen… - …, 2021 - academic.oup.com
CircRNAs (circular RNAs), recently identified as a critical regulator in tumorigenesis,
participate in CRC (colorectal cancer) growth. However, the role of hsa_circRNA_002144 in …

Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression

Z Chen, R Ren, D Wan, Y Wang, X Xue, M Jiang… - Oncogene, 2019 - nature.com
CircRNAs have been reported to exert momentous roles in regulating pathophysiological
process and guiding clinical diagnosis and treatment in colorectal cancer (CRC). However …

[HTML][HTML] circCUL2 regulates gastric cancer malignant transformation and cisplatin resistance by modulating autophagy activation via miR-142-3p/ROCK2

L Peng, H Sang, S Wei, Y Li, D Jin, X Zhu, X Li, Y Dang… - Molecular cancer, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs)
and can modulate gene expression by binding to miRNAs; further, circRNAs have been …

[HTML][HTML] RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer

XN Li, ZJ Wang, CX Ye, BC Zhao, ZL Li… - Journal of Experimental & …, 2018 - Springer
Abstract Background Circular RNA (circRNA) is a novel class of noncoding RNAs with
functions in various pathophysiological activities. However, the expression profiles and …

A novel circFMN2 promotes tumor proliferation in CRC by regulating the miR-1182/hTERT signaling pathways

Y Li, C Li, R Xu, Y Wang, D Li, B Zhang - Clinical Science, 2019 - portlandpress.com
Abstract Background: Circular RNAs (circRNAs) are a class of non-coding RNAs broadly
expressed in cells of various species. However, the molecular mechanisms that link …

[HTML][HTML] Circular RNA circCTNNA1 promotes colorectal cancer progression by sponging miR-149-5p and regulating FOXM1 expression

P Chen, Y Yao, N Yang, L Gong, Y Kong, A Wu - Cell death & disease, 2020 - nature.com
Circular RNAs (circRNAs) are an emerging class of non-coding RNAs, identified to
participate in multiple malignancies. Nevertheless, the clinical significance, biological …