Background Dysfunction or deficiency of corneal epithelium results in vision impairment or
blindness in severe cases. The rapid and effective regeneration of corneal epithelial cells …

Limbal stem cells (LSCs) reside in the basal layer of limbal epithelial cells (LECs). They are
crucial for maintenance of corneal epithelium homeostasis and corneal wound healing …

The transparent corneal epithelium in the eye is maintained through the homeostasis
regulated by limbal stem cells (LSCs), while the nontransparent epidermis relies on …

Purpose This study aimed to uncover novel cell types in heterogenous basal limbus of
human cornea for identifying LSC at single cell resolution. Methods Single cells of human …

The accessibility and transparency of the cornea permit robust stem cell labeling and in vivo
cell fate mapping. Limbal epithelial stem cells (LSCs) that renew the cornea are traditionally …

Limbus-derived stromal/mesenchymal stem cells (LMSCs) are vital for corneal homeostasis
and wound healing. However, despite multiple pre-clinical and clinical studies reporting the …

The corneal epithelium is composed of nonkeratinized stratified squamous cells and has a
significant turnover rate. Limbal integrity is vital to maintain the clarity and avascularity of the …

Purpose: Wound healing of the corneal epithelium mainly involves two types of cells: limbal
stem/progenitor cells (LSCs) and differentiated central corneal epithelial cells (CECs). The …

The corneal epithelium is composed of stratified squamous epithelial cells on the outer
surface of the eye, which acts as a protective barrier and is critical for clear and stable vision …

The corneal epithelium acts as a barrier to pathogens entering the eye; corneal epithelial
cells are continuously renewed by uni-potent, quiescent limbal stem cells (LSCs) located at …