Energy dissipation in brown adipose tissue: from mice to men

MJ Vosselman, WD van Marken Lichtenbelt… - Molecular and cellular …, 2013 - Elsevier
In rodents, brown adipose tissue (BAT) is a metabolic organ that produces heat in response
to cold and dietary intake through mitochondrial uncoupling. For long time, BAT was …

[HTML][HTML] Brown adipose tissue and thermogenesis

A Fenzl, FW Kiefer - Hormone molecular biology and clinical …, 2014 - degruyter.com
The growing understanding of adipose tissue as an important endocrine organ with multiple
metabolic functions has directed the attention to the (patho) physiology of distinct fat depots …

Brown adipose tissue: research milestones of a potential player in human energy balance and obesity

B Zafrir - Hormone and Metabolic Research, 2013 - thieme-connect.com
Obesity and diabetes mellitus are worldwide epidemics driven by the disruption in energy
balance. In recent years, it was discovered that functional brown adipose tissue (BAT), once …

An update on brown adipose tissue biology: a discussion of recent findings

RC Gaspar, JR Pauli, GI Shulman… - American Journal of …, 2021 - journals.physiology.org
Brown adipose tissue (BAT) has been encouraged as a potential treatment for obesity and
comorbidities due to its thermogenic activity capacity and contribution to energy expenditure …

Studying Brown Adipose Tissue in a Human in vitro Context

I Samuelson, A Vidal-Puig - Frontiers in endocrinology, 2020 - frontiersin.org
New treatments for obesity and associated metabolic disease are increasingly warranted
with the growth of the obesity pandemic. Brown adipose tissue (BAT) may represent a …

A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis

S Kajimura, M Saito - Annual review of physiology, 2014 - annualreviews.org
Brown adipose tissue (BAT) is specialized to dissipate chemical energy in the form of heat
as a defense against cold and excessive feeding. Interest in the field of BAT biology has …

Mechanisms of impaired brown adipose tissue recruitment in obesity

M Alcalá, M Calderon-Dominguez, D Serra… - Frontiers in …, 2019 - frontiersin.org
Brown adipose tissue (BAT) dissipates energy to produce heat. Thus, it has the potential to
regulate body temperature by thermogenesis. For the last decade, BAT has been in the …

MECHANISMS IN ENDOCRINOLOGY: Brown adipose tissue in humans: regulation and metabolic significance

M Thuzar, KKY Ho - European Journal of Endocrinology, 2016 - academic.oup.com
The recent discovery that functional brown adipose tissue (BAT) persists in adult humans
has enkindled a renaissance in metabolic research, with a view of harnessing its …

Thermogenic brown and beige/brite adipogenesis in humans

R Cereijo, M Giralt, F Villarroya - Annals of medicine, 2015 - Taylor & Francis
Evidence from rodents established an important role of brown adipose tissue (BAT) in
energy expenditure. Moreover, to sustain thermogenesis, BAT has been shown to be a …

The significance of beige and brown fat in humans

FW Kiefer - Endocrine connections, 2017 - ec.bioscientifica.com
Promotion of brown adipose tissue (BAT) activity or browning of white adipose tissue has
shown great potential as anti-obesity strategy in numerous preclinical models. The discovery …