Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

E Yagdi, C Cerella, M Dicato, M Diederich - Food and Chemical Toxicology, 2016 - Elsevier
In vitro and in vivo studies reported the anti-cancer potential of organosulfur compounds
(OSCs) as they trigger biological effects leading to cell cycle arrest with accumulation of cells …

Naturally occurring reactive sulfur species, their activity against Caco-2 cells, and possible modes of biochemical action

A Anwar, T Burkholz, C Scherer, M Abbas… - Journal of Sulfur …, 2008 - Taylor & Francis
Natural sulfur compounds from plants, bacteria, fungi, and animals frequently exhibit
interesting biological activities, such as antioxidant, antimicrobial, and anticancer activity …

Diallylpolysulfides induce growth arrest and apoptosis

C Busch, C Jacob, A Anwar… - International …, 2010 - spandidos-publications.com
Garlic-derived organo sulphur compounds such as diallylsulfides provide a significant
protection against carcinogenesis. Chemically synthesized, and highly pure diallylsulfides …

Chemical properties and mechanisms determining the anti-cancer action of garlic-derived organic sulfur compounds

C Cerella, M Dicato, C Jacob… - Anti-Cancer Agents in …, 2011 - ingentaconnect.com
Organic sulfur compounds (OSCs) derived from plants, fungi or bacteria can serve as
chemopreventive and/or chemotherapeutic agents and have been attracting medical and …

Role of H2S Donors in Cancer Biology

ZW Lee, LW Deng - … , Biochemistry and Pharmacology of Hydrogen Sulfide, 2015 - Springer
Hydrogen sulfide (H 2 S) donors including organosulfur compounds (OSC), inorganic sulfide
salts, and synthetic compounds are useful tools in studies to elucidate the effects of H 2 S in …

Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells

Y Pei, B Wu, Q Cao, L Wu, G Yang - Toxicology and applied pharmacology, 2011 - Elsevier
Hydrogen sulfide (H2S) is a novel gasotransmitter that regulates cell proliferation and other
cellular functions. Sulforaphane (SFN) is a sulfur-containing compound that exhibits …

Synthetic polysulfane derivatives induce cell cycle arrest and apoptotic cell death in human hematopoietic cancer cells

B Czepukojc, AK Baltes, C Cerella, M Kelkel… - Food and Chemical …, 2014 - Elsevier
Natural polysulfanes including diallyltrisulfide (DATS) and diallyltetrasulfide (DATTS) from
garlic possess antimicrobial, chemopreventive and anticancer properties. However these …

The effects of garlic‐derived sulfur compounds on cell proliferation, caspase 3 activity, thiol levels and anaerobic sulfur metabolism in human hepatoblastoma HepG2 …

M Iciek, I Kwiecień, G Chwatko… - Cell biochemistry …, 2012 - Wiley Online Library
The aim of the present studies was to determine whether the mechanism of biological action
of garlic‐derived sulfur compounds in human hepatoma (HepG2) cells can be dependent on …

Vegetable organosulfur compounds and their health promoting effects

S Petropoulos, F Di Gioia… - Current pharmaceutical …, 2017 - ingentaconnect.com
Background: Trends in modern pharmaceutical science show an increase in demand for
new drugs and diet supplements derived from natural products, while during the last …

[HTML][HTML] The multifaceted roles of sulfane sulfur species in cancer-associated processes

K Zuhra, CS Tomé, E Forte, JB Vicente… - Biochimica et Biophysica …, 2021 - Elsevier
Sulfane sulfur species comprise a variety of biologically relevant hydrogen sulfide (H 2 S)-
derived species, including per-and poly-sulfidated low molecular weight compounds and …