Background Decellularization methods using anionic detergents have been applied to
engineered tissues for eliminating tissue immunogenicity. Sodium deoxycholate is a water …

The increasing urgency for replacement of pathological heart valves is a major stimulus for
research on alternatives to glutaraldehyde‐treated grafts. New xenogeneic acellular heart …

Background: Cellular remnants in the bioprosthetic heart valve are known to be related to a
host's immunologic response and they can form the nidus for calcification. The extracellular …

To optimize rabbit kidney decellularization protocol, using sodium dodecyl sulfate (SDS) as
a commonly used detergent, a methylene blue based assay was employed for detecting the …

Methods Homogenized BP or PAV were injected into rabbits to generate immune serum
towards these tissues. Soluble proteins were extracted from untreated BP and PAV …

Detergents are powerful agents for tissue decellularization. Despite this, the high toxicity of
detergent residua can be a major limitation. This study evaluated the efficacy of detergent …

INTRODUCTION: Decellularized cryopreserved allograft vascular tissue may provide a
nonimmunogenic scaffold that is suitable for repopulation by cells from a variety of sources …

The clinical use of decellularized cardiac valve allografts is increasing. Long‐term data will
be required to determine whether they outperform conventional cryopreserved allografts …

Background Various detergent‐based protocols are used to remove cells and cellular debris
in porcine aortic valve (PAV). However, the removal of antigenic cellular components has …

An automatic decellularization device was developed to perfuse and decellularize male rats'
kidneys using both sodium lauryl ether sulfate (SLES) and sodium dodecyl sulfate (SDS) …