A dopaminergic basis for fear extinction

R Kalisch, AMV Gerlicher, S Duvarci - Trends in cognitive sciences, 2019 - cell.com
It is a joyous relief when an event we dread fails to materialize. In fear extinction, the
appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the …

[HTML][HTML] Dopamine in fear extinction

XI Salinas-Hernández, S Duvarci - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
The ability to extinguish fear memories when threats are no longer present is critical for
adaptive behavior. Fear extinction represents a new learning process that eventually leads …

[HTML][HTML] Dopamine-dependent prefrontal reactivations explain long-term benefit of fear extinction

AMV Gerlicher, O Tüscher, R Kalisch - Nature communications, 2018 - nature.com
Fear extinction does not prevent post-traumatic stress or have long-term therapeutic benefits
in fear-related disorders unless extinction memories are easily retrieved at later encounters …

[HTML][HTML] A dopaminergic switch for fear to safety transitions

R Luo, A Uematsu, A Weitemier, L Aquili… - Nature …, 2018 - nature.com
Overcoming aversive emotional memories requires neural systems that detect when fear
responses are no longer appropriate so that they can be extinguished. The midbrain ventral …

[HTML][HTML] Activation of D1/5 dopamine receptors: a common mechanism for enhancing extinction of fear and reward-seeking behaviors

AD Abraham, KA Neve, KM Lattal - Neuropsychopharmacology, 2016 - nature.com
Dopamine is critical for many processes that drive learning and memory, including
motivation, prediction error, incentive salience, memory consolidation, and response output …

Dopamine and extinction: a convergence of theory with fear and reward circuitry

AD Abraham, KA Neve, KM Lattal - Neurobiology of learning and memory, 2014 - Elsevier
Research on dopamine lies at the intersection of sophisticated theoretical and
neurobiological approaches to learning and memory. Dopamine has been shown to be …

Single dose of l-dopa makes extinction memories context-independent and prevents the return of fear

J Haaker, S Gaburro, A Sah… - Proceedings of the …, 2013 - National Acad Sciences
Traumatic events can engender persistent excessive fear responses to trauma reminders
that may return even after successful treatment. Extinction, the laboratory analog of behavior …

[HTML][HTML] On the role of subsecond dopamine release in conditioned avoidance

EB Oleson, JF Cheer - Frontiers in neuroscience, 2013 - frontiersin.org
Using shock avoidance procedures to study conditioned behavioral responses has a rich
history within the field of experimental psychology. Such experiments led to the formulation …

The learning of fear extinction

C Furini, J Myskiw, I Izquierdo - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Recent work on the extinction of fear-motivated learning places emphasis on its putative
circuitry and on its modulation. Extinction is the learned inhibition of retrieval of previously …

Dopamine regulation of contextual fear and associated neural circuit function

C Stubbendorff, CW Stevenson - European Journal of …, 2021 - Wiley Online Library
Learning to associate certain contexts with threat and adapting to changing environmental
contingencies by learning that such contexts are no longer associated with threat are both …