Quantification of Vitamin D3 in Feed, Food, and Pharmaceuticals Using High-Performance Liquid Chromatography/Tandem Mass Spectrometry

HS Schadt, R Gössl, N Seibel… - Journal of AOAC …, 2012 - academic.oup.com
A rapid, sensitive, and selective method for the quantification of vitamin D3 (cholecalciferol)
in solid and liquid food, feed, and tablets based on HPLC/MS/MS has been developed and …

Vitamin D: Current challenges between the laboratory and clinical practice

L Máčová, M Bičíková - Nutrients, 2021 - mdpi.com
Vitamin D is a micronutrient with pleiotropic effects in humans. Due to sedentary lifestyles
and increasing time spent indoors, a growing body of research is revealing that vitamin D …

Sample preparation techniques for extraction of vitamin D metabolites from non-conventional biological sample matrices prior to LC–MS/MS analysis

A Alexandridou, DA Volmer - Analytical and Bioanalytical Chemistry, 2022 - Springer
The determination of vitamin D metabolites as status marker or for diagnostic purposes is
almost entirely conducted from blood serum or plasma. Other biological matrices, however …

Stability-Indicating HPLC–UV Method for Vitamin D3 Determination in Solutions, Nutritional Supplements and Pharmaceuticals

Ž Temova, R Roškar - Journal of Chromatographic Science, 2016 - academic.oup.com
A simple and fast high-performance liquid chromatography method with UV detection for
determination of vitamin D3 in stability studies as well as in solutions, nutritional …

Development and validation of an LC–MS/MS based method for quantification of 25 hydroxyvitamin D2 and 25 hydroxyvitamin D3 in human serum and plasma

SW Zhang, W Jian, S Sullivan, B Sankaran… - … of Chromatography B, 2014 - Elsevier
Vitamin D deficiency is increasing in the general population and has become a serious
public health risk globally. As a reliable clinical indicator of vitamin status, 25 hydroxyvitamin …

Simultaneous quantification of four vitamin D metabolites in human serum using high performance liquid chromatography tandem mass spectrometry for vitamin D …

S Baecher, A Leinenbach, JA Wright, S Pongratz… - Clinical …, 2012 - Elsevier
OBJECTIVES: For quantification of 25-hydroxyvitamin D3 (25OH-D3), 25-hydroxyvitamin D2
(25OH-D2), 3-epi-25-hydroxyvitamin D3 (3-epi-25OH-D3) and 24R, 25-dihydroxyvitamin D3 …

Assessing vitamin D metabolism–four decades of experience

M Herrmann - Clinical Chemistry and Laboratory Medicine (CCLM), 2023 - degruyter.com
One hundred years ago, the role of vitamin D for bone mineralization and the prevention of
rickets was discovered. Vitamin D comprises a group of over 50 metabolites with multiple …

Analysis of vitamin D metabolic markers by mass spectrometry: current techniques, limitations of the “gold standard” method, and anticipated future directions

DA Volmer, LRBC Mendes… - Mass spectrometry …, 2015 - Wiley Online Library
Vitamin D compounds belong to a group of secosteroids, which occur naturally as vitamin
D3 in mammals and D2 in plants. Vitamin D is vital for bone health but recent studies have …

A RAPID METHOD FOR DETERMINATION OF VITAMINS D2 AND D3 IN PHARMACEUTICAL PREPARATIONS BY HPLC

K Sarioglu, SS Celebi, M Mutlu - Journal of liquid chromatography …, 2001 - Taylor & Francis
In this study, a rapid, simple, and economical reversed phase liquid chromatographic
method was described for the determination of vitamin D2 and vitamin D3 in pharmaceutical …

Serum Vitamin D Metabolites by HPLC-MS/MS Combined with Differential Ion Mobility Spectrometry: Aspects of Sample Preparation without Derivatization

L Usoltseva, V Ioutsi, Y Panov, M Antsupova… - International Journal of …, 2023 - mdpi.com
In current clinical practice, a thorough understanding of vitamin D metabolism is in high
demand both for patients with various diseases and for healthy individuals. Analytical …