A human nasal cavity was reconstructed from CT scans to make a Computational Fluid
Dynamics (CFD) model. With this model, fluid flow and inhalation of aerosol analysis can be …

The human nasal passages effectively filter particles from inhaled air. This prevents harmful
pollutants from reaching susceptible pulmonary airways, but may leave the nasal mucosa …

The human nasal cavities, each with an effective length of only 10cm, feature a wide array of
basic flow phenomena due to their complex geometries. Dependent on such airflow fields …

Knowledge regarding particle deposition processes in the nasal cavity is important in
aerosol therapy and inhalation toxicology applications. This paper presents a comparative …

Effective nasal drug delivery is highly dependent on the delivery of drug from the nasal spray
device. Atomisation of liquid spray occurs through the internal atomizer that can produce …

The complex nasal structure poses obstacles for efficient nasal drug administration beyond
the nasal valve, especially when targeting the olfactory region. This study numerically …

Purpose: The objective of this study was to develop a computational fluid dynamics (CFD)
model to predict the deposition, dissolution, clearance, and absorption of pharmaceutical …

The nasal epithelium is an important target for drug delivery to the nose and secondary
organs such as the brain via the olfactory bulb. For both topical and brain delivery, the …

The transfer and deposition of particles in the respiratory system is of major interest to the
scientific and medical community in terms of the development of targeted drug delivery …

A computational model for flow and particle deposition in a three-dimensional
representation of the human nasal cavity is developed. Simulations of steady state and …