Chloroquine and hydroxychloroquine in the management of COVID-19: much kerfuffle but little evidence

M Roustit, R Guilhaumou, M Molimard, MD Drici… - Therapies, 2020 - Elsevier
Chloroquine and hydroxychloroquine are drugs that have shown in vitro activity on the
replication of certain coronaviruses. In the context of the SARS-Cov-2 epidemic, the virus …

[HTML][HTML] Rethinking the role of hydroxychloroquine in the treatment of COVID‐19

EA Meyerowitz, AGL Vannier, MGN Friesen… - The FASEB …, 2020 - ncbi.nlm.nih.gov
There are currently no proven or approved treatments for coronavirus disease 2019 (COVID‐
19). Early anecdotal reports and limited in vitro data led to the significant uptake of …

Role of chloroquine and hydroxychloroquine in the treatment of COVID-19 infection-a systematic literature review

KM Kapoor, A Kapoor - Medrxiv, 2020 - medrxiv.org
Background Coronavirus pandemic is currently a global public health emergency. At
present, no pharmacological treatment is known to treat this condition, and there is a need to …

Emergency authorization of chloroquine and hydroxychloroquine for treatment of COVID-19

CR Piszczatoski, J Powell - Annals of Pharmacotherapy, 2020 - journals.sagepub.com
The world is suffering a respiratory pandemic disease caused by a novel coronavirus (2019-
nCoV), commonly known as COVID-19 (coronavirus disease 2019). The Food and Drug …

[HTML][HTML] Chloroquine and COVID-19–a potential game changer?

BRH Sturrock, TJT Chevassut - Clinical Medicine, 2020 - Elsevier
The novel coronavirus SARS-CoV-2, causing the disease COVID-19, first emerged in
Wuhan, China in December 2019 and has now spread to 203 countries or territories …

Chloroquine and hydroxychloroquine in coronavirus disease 2019 (COVID-19). Facts, fiction and the hype: a critical appraisal

MS Khuroo - International journal of antimicrobial agents, 2020 - Elsevier
Abstract The coronavirus infection (COVID-19) has turned into a global catastrophe and
there is an intense search for effective drug therapy. Of all the potential therapies …

Use of hydroxychloroquine and chloroquine in patients with COVID-19: a meta-analysis of randomized clinical trials

PR Bignardi, CS Vengrus, BM Aquino… - Pathogens and Global …, 2021 - Taylor & Francis
ABSTRACT COVID-19 has quickly become a public health problem worldwide, and
treatment for this new disease is needed. Hydroxychloroquine is an antimalarial that in vitro …

Hydroxychloroquine and chloroquine for COVID-19 infection. Rapid systematic review

RL Pacheco, R Riera - Journal of Evidence-Based Healthcare, 2020 - bahiana.edu.br
CONTEXT: Based on the results of preliminary studies, the off-label use of
hydroxychloroquine for COVID-19 infection has been observed in practice. OBJECTIVES: To …

Chloroquine and hydroxychloroquine to treat COVID-19: between hope and caution

B Mégarbane - Clinical Toxicology, 2021 - Taylor & Francis
To the editor, Since December 2019, a pandemic outbreak of emerging coronavirus disease
(COVID-19) due to SARS-CoV-2 is spreading, resulting in exponentially increasing numbers …

[HTML][HTML] Chloroquine, hydroxychloroquine, and COVID-19: Systematic review and narrative synthesis of efficacy and safety

M Takla, K Jeevaratnam - Saudi Pharmaceutical Journal, 2020 - Elsevier
The COVID-19 pandemic has required clinicians to urgently identify new treatment options
or the re-purposing of existing drugs. Of particular interest are chloroquine (CQ) and …