SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

A cytokine super cyclone in COVID-19 patients with risk factors: the therapeutic potential of BCG immunization

BS Johnson, M Laloraya - Cytokine & growth factor reviews, 2020 - Elsevier
The seventh human coronavirus SARS-CoV2 belongs to the cluster of extremely pathogenic
coronaviruses including SARS-CoV and MERS-CoV, which can cause fatal lower …

The Role of Inflammatory Cytokines (Interleukin-1 and Interleukin-6) as a Potential Biomarker in the Different Stages of COVID-19 (Mild, Severe, and Critical)

M Ghofrani Nezhad, G Jami, O Kooshkaki… - Journal of Interferon & …, 2023 - liebertpub.com
Cytokine storm refers to the overproduction of immune and inflammatory cells and their
proteins (cytokines)[interleukin (IL)-1 and IL-6] causing acute respiratory distress syndrome …

[HTML][HTML] Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

[HTML][HTML] Calming the inflammatory storm in severe COVID-19 infections: Role of biologics-A narrative review

D Banji, SS Alqahtani, OJF Banji… - Saudi Pharmaceutical …, 2021 - Elsevier
The risk of Coronavirus infection continues, and the fear of resurgence indicates the lack of a
successful therapeutic strategy. In severe COVID-19 infection, many immune cells and their …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

Advances in immunotherapy for COVID-19: A comprehensive review

M Masoomikarimi, B Garmabi, J Alizadeh… - International …, 2021 - Elsevier
COVID-19 is an acute respiratory syndrome caused by SARS-COV-2 which has now
become a huge pandemic worldwide. The immunopathogenesis of COVID-19 has been …

[HTML][HTML] Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
Objective To describe the laboratory parameters and biomarkers of the cytokine storm
syndrome associated with severe and fatal COVID-19 cases. Methods A search with …

[HTML][HTML] Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies

G Zhou, S Chen, Z Chen - Frontiers of medicine, 2020 - Springer
Since the outbreak of the COVID-19 pandemic in early December 2019, 81 174 confirmed
cases and 3242 deaths have been reported in China as of March 19, 2020. The Chinese …

Comparison of the characteristics of cytokine storm and immune response induced by SARS-CoV, MERS-CoV, and SARS-CoV-2 infections

T Liu, M Feng, Z Wen, Y He, W Lin… - Journal of inflammation …, 2021 - Taylor & Francis
Cytokine storm (CS) is a significant cause of death in patients with severe coronavirus
pneumonia. Excessive immune–inflammatory reaction, many inflammatory cell infiltration …