[HTML][HTML] Regional functional connectivity predicts distinct cognitive impairments in Alzheimer's disease spectrum

KG Ranasinghe, LB Hinkley, AJ Beagle, D Mizuiri… - NeuroImage: Clinical, 2014 - Elsevier
Understanding neural network dysfunction in neurodegenerative disease is imperative to
effectively develop network-modulating therapies. In Alzheimer's disease (AD), cognitive …

Abnormal Resting‐State Functional Connectivity Strength in Mild Cognitive Impairment and Its Conversion to Alzheimer's Disease

Y Li, X Wang, Y Li, Y Sun, C Sheng, H Li, X Li… - Neural …, 2016 - Wiley Online Library
Individuals diagnosed with mild cognitive impairment (MCI) are at high risk of transition to
Alzheimer's disease (AD). However, little is known about functional characteristics of the …

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI

MD Greicius, G Srivastava… - Proceedings of the …, 2004 - National Acad Sciences
Recent functional imaging studies have revealed coactivation in a distributed network of
cortical regions that characterizes the resting state, or default mode, of the human brain …

Patterns of spontaneous brain activity in amyotrophic lateral sclerosis: a resting-state FMRI study

CY Luo, Q Chen, R Huang, XP Chen, K Chen… - 2012 - journals.plos.org
By detecting spontaneous low-frequency fluctuations (LFF) of blood oxygen level–
dependent (BOLD) signals, resting-state functional magnetic resonance imaging (rfMRI) …

Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest

VG van de Ven, E Formisano, D Prvulovic… - Human brain …, 2004 - Wiley Online Library
Cortical functional connectivity, as indicated by the concurrent spontaneous activity of
spatially segregated regions, is being studied increasingly because it may determine the …

Resting-state oscillatory brain dynamics in Alzheimer disease

W de Haan, CJ Stam, BF Jones… - Journal of Clinical …, 2008 - journals.lww.com
Altered oscillatory brain activity in Alzheimer disease (AD) may reflect underlying
neuropathological changes, and its characterization might lead to new diagnostic …

Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: an fMRI study

SARB Rombouts, F Barkhof, R Goekoop… - Human brain …, 2005 - Wiley Online Library
Activity and reactivity of the default mode network in the brain was studied using functional
magnetic resonance imaging (fMRI) in 28 nondemented individuals with mild cognitive …

Relation between medial temporal atrophy and functional brain activity during memory processing in Alzheimer's disease: a combined MRI and SPECT study

GEJ Garrido, SS Furuie, CA Buchpiguel… - Journal of Neurology …, 2002 - jnnp.bmj.com
Objective: To investigate the relation between atrophy of the hippocampal region and brain
functional patterns during episodic memory processing in Alzheimer's disease. Patients and …

Delayed rather than decreased BOLD response as a marker for early Alzheimer's disease

SARB Rombouts, R Goekoop, CJ Stam, F Barkhof… - Neuroimage, 2005 - Elsevier
Functional MRI (fMRI) in established Alzheimer's disease (AD) shows regionally altered
blood oxygenation level dependent (BOLD) responses. Mild cognitive impairment (MCI) is …

Resting state functional connectivity in preclinical Alzheimer's disease

YI Sheline, ME Raichle - Biological psychiatry, 2013 - Elsevier
There has been a dramatic increase in the number of studies using resting state functional
magnetic resonance imaging (rs-fMRI), a recent addition to imaging analysis techniques …