[HTML][HTML] Fluoroquinolones or macrolides in combination with β-lactams in adult patients hospitalized with community acquired pneumonia: a systematic review and …

KZ Vardakas, KK Trigkidis, ME Falagas - Clinical Microbiology and …, 2017 - Elsevier
Objective The best treatment option for hospitalized patients with community-acquired
pneumonia (CAP) has not been defined. The effectiveness of β-lactam/fluoroquinolone …

Fluoroquinolones or macrolides alone versus combined with β-lactams for adults with community-acquired pneumonia: systematic review and meta-analysis

A Raz-Pasteur, D Shasha, M Paul - International journal of antimicrobial …, 2015 - Elsevier
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality. This
review compared two of the main treatment alternatives: quinolone or macrolide …

Monotherapy versus combination therapy in patients hospitalized with community-acquired pneumonia

M Kolditz, M Halank, G Höffken - Treatments in respiratory medicine, 2006 - Springer
Current international guidelines for the management of community acquired pneumonia
(CAP) recommend therapy with a β-lactam plus a macrolide or a 'respiratory'fluoroquinolone …

Respiratory fluoroquinolone monotherapy versus β-lactam plus macrolide combination therapy for hospitalized adults with community-acquired pneumonia: A …

SH Choi, A Cesar, TAC Snow, N Saleem… - International Journal of …, 2023 - Elsevier
Introduction Guidelines recommend respiratory fluoroquinolone monotherapy or β-lactam
plus macrolide combination therapy as first-line options for hospitalized adults with mild to …

The dilemma of monotherapy or combination therapy in community‐acquired pneumonia

KZ Vardakas, KK Trigkidis… - European journal of …, 2017 - Wiley Online Library
Scope To study the factors associated with mortality in hospitalized patients with community‐
acquired pneumonia treated with monotherapy or combination therapy. Methods PubMed …

Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: a systematic review and meta-analysis

L Asadi, WI Sligl, DT Eurich, IN Colmers… - Clinical Infectious …, 2012 - academic.oup.com
Background. Macrolides are used to treat pneumonia despite increasing antimicrobial
resistance. However, the immunomodulatory properties of macrolides may have a favorable …

Is β-lactam plus macrolide more effective than β-lactam plus fluoroquinolone among patients with severe community-acquired pneumonia?: a systemic review and …

JH Lee, HJ Kim, YH Kim - Journal of Korean medical science, 2017 - synapse.koreamed.org
Adding either macrolide or fluoroquinolone (FQ) to β-lactam has been recommended for
patients with severe community-acquired pneumonia (CAP). However, due to the limited …

[HTML][HTML] Macrolides vs. quinolones for community-acquired pneumonia: meta-analysis of randomized controlled trials

K Skalsky, D Yahav, A Lador, N Eliakim-Raz… - Clinical Microbiology …, 2013 - Elsevier
The relative efficacy, safety and ecological implications of macrolides vs. quinolones in the
treatment of community-acquired pneumonia (CAP) are debatable. We performed a …

How good is the evidence for the recommended empirical antimicrobial treatment of patients hospitalized because of community-acquired pneumonia? A systematic …

JJ Oosterheert, MJM Bonten, E Hak… - Journal of …, 2003 - academic.oup.com
Background: For years, monotherapy with a β-lactam antibiotic (penicillin, amoxicillin or
second-generation cephalosporin) was recommended as empirical therapy for patients with …

Comparison of β-lactam and macrolide combination therapy versus fluoroquinolone monotherapy in hospitalized Veterans Affairs patients with community-acquired …

TP Lodise, A Kwa, L Cosler, R Gupta… - Antimicrobial agents …, 2007 - Am Soc Microbiol
Data comparing the treatment outcomes of the two most frequently recommended empirical
antibiotic regimens for community-acquired pneumonia (CAP)—combination therapy with an …