Trypanosoma brucei, the causative agent of African sleeping sickness, encodes three
cysteine homologues (Px I-III) of classical selenocysteine-containing glutathione …

Trypanosoma brucei, the causative agent of African sleeping sickness, encodes three nearly
identical genes for cysteine-homologues of the selenocysteine-containing glutathione …

Trypanosoma brucei, the causative agent of African sleeping sickness, encodes three nearly
identical cysteine homologues of the classical selenocysteine-containing glutathione …

Trypanosoma brucei, the causative agent of African sleeping sickness, has three nearly
identical genes encoding cysteine homologues of classical selenocysteine-containing …

Tb TDPX (Trypanosoma brucei tryparedoxin-dependent peroxidase) is a genetically
validated drug target in the fight against African sleeping sickness. Despite its similarity to …

Tryparedoxin peroxidase (TryP) is a recently discovered 2Cys-peroxiredoxin involved in
defence against oxidative stress in parasitic trypanosomatids. The crystal structure of …

Trypanothione [N 1, N 8-bis (glutathionyl) spermidine, T (SH) 2], discovered in 1985 by
Fairlamb and Cerami, 1 is the main low molecular weight thiol in trypanosomatids of the …

Tryparedoxin (TXN) has recently been discovered as a constituent of the complex
peroxidase system in the trypanosomatid Crithidia fasciculata [Nogoceke et al.(1997) Biol …

Trypanothione-dependent metabolism of hydroperoxides in the trypanosomatids is a unique
system involving trypanothione reductase, tryparedoxin and tryparedoxin peroxidase [1] …

Tryparedoxin peroxidases (TXNPx) are peroxiredoxintype enzymes that detoxify
hydroperoxides in trypanosomatids. Reduction equivalents are provided by trypanothione [T …