[HTML][HTML] Salvianolic acid C potently inhibits SARS-CoV-2 infection by blocking the formation of six-helix bundle core of spike protein
C Yang, X Pan, X Xu, C Cheng, Y Huang, L Li… - Signal transduction and …, 2020 - nature.com
The pandemic of COVID-19 caused by SARS-CoV-2 infection has posed a serious threat to
global public health and the economy. Up to now, although several potentially effective …
global public health and the economy. Up to now, although several potentially effective …
[HTML][HTML] Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high …
S Xia, M Liu, C Wang, W Xu, Q Lan, S Feng, F Qi, L Bao… - Cell research, 2020 - nature.com
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in
Wuhan, China has posed a serious threat to global public health. To develop specific anti …
Wuhan, China has posed a serious threat to global public health. To develop specific anti …
[HTML][HTML] Identification and evaluation of the inhibitory effect of Prunella vulgaris extract on SARS-coronavirus 2 virus entry
Until now, antiviral therapeutic agents are still urgently required for treatment or prevention
of SARS-coronavirus 2 (SCoV-2) virus infection. In this study, we established a sensitive …
of SARS-coronavirus 2 (SCoV-2) virus infection. In this study, we established a sensitive …
Three salvianolic acids inhibit 2019‐nCoV spike pseudovirus viropexis by binding to both its RBD and receptor ACE2
S Hu, J Wang, Y Zhang, H Bai, C Wang… - Journal of medical …, 2021 - Wiley Online Library
Since December 2019, the new coronavirus (also known as severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2, 2019‐nCoV])—induced disease, COVID‐19, has …
syndrome coronavirus 2 [SARS‐CoV‐2, 2019‐nCoV])—induced disease, COVID‐19, has …
[HTML][HTML] A novel cyclic γ-AApeptide-based long-acting pan-coronavirus fusion inhibitor with potential oral bioavailability by targeting two sites in spike protein
The receptor-binding domain (RBD) in S1 subunit and heptad repeat 1 (HR1) domain in S2
subunit of SARS-CoV-2 spike (S) protein are the targets of neutralizing antibodies (nAbs) …
subunit of SARS-CoV-2 spike (S) protein are the targets of neutralizing antibodies (nAbs) …
Sertraline is an effective SARS-CoV-2 entry inhibitor targeting the spike protein
Y Chen, Y Wu, S Chen, Q Zhan, D Wu, C Yang… - Journal of …, 2022 - Am Soc Microbiol
The global spread of the novel coronavirus severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and the continuously emerging new variants underscore an urgent need for …
(SARS-CoV-2) and the continuously emerging new variants underscore an urgent need for …
[HTML][HTML] Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Similar to severe acute respiratory syndrome (SARS)-CoV, 2019-nCoV belongs to lineage B
betacoronavirus, and it has the ability to utilize human angiotensin-converting enzyme 2 …
betacoronavirus, and it has the ability to utilize human angiotensin-converting enzyme 2 …
Identification, optimization, and biological evaluation of 3-O-β-chacotriosyl ursolic acid derivatives as novel SARS-CoV-2 entry inhibitors by targeting the prefusion …
H Li, C Cheng, S Shi, Y Wu, Y Gao, Z Liu, M Liu… - European Journal of …, 2022 - Elsevier
The COVID-19 pandemic generates a global threat to public health and continuously
emerging SARS-CoV-2 variants bring a great challenge to the development of both vaccines …
emerging SARS-CoV-2 variants bring a great challenge to the development of both vaccines …
Design of potent membrane fusion inhibitors against SARS-CoV-2, an emerging coronavirus with high fusogenic activity
Y Zhu, D Yu, H Yan, H Chong, Y He - Journal of virology, 2020 - Am Soc Microbiol
ABSTRACT The 2019 coronavirus disease (COVID-19), caused by the emerging severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed serious threats to …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has posed serious threats to …
[HTML][HTML] Identification of bis-benzylisoquinoline alkaloids as SARS-CoV-2 entry inhibitors from a library of natural products
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a major public health issue. The spike (S) protein mutation …
coronavirus 2 (SARS-CoV-2) is a major public health issue. The spike (S) protein mutation …
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