A wide range of techniques have been employed to examine the quaternary structure of G-
protein-coupled receptors (GPCRs). Although it is well established that homo-dimerisation is …

Recently, many G-protein-coupled receptors (GPCRs) have been demonstrated to form
constitutive dimers consisting of identical or distinct monomeric subunits. The discovery of …

G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …

The classical idea that G‐protein‐coupled receptors (GPCRs) function as monomeric
entities has been unsettled by the emerging concept of GPCR dimerization. Recent findings …

G protein-coupled receptors (GPCRs) represent the major target for drug development.
Although these receptors can activate their cognate G-proteins in a monomeric form, it is …

Communication between cells requires key and specialized signaling systems, like G-
protein-coupled receptors (GPCRs). Cells coexpress a large number of different GPCRs, the …

Although classical models predict that G-protein-coupled receptors (GPCRs) function as
monomers, several recent studies acknowledge that GPCRs exist as dimeric or oligomeric …

Although highly controversial just a few years ago, the idea that G‐protein‐coupled
receptors (GPCRs) may undergo homo‐oligomerization or hetero‐oligomerization has …

Initially considered as strict and rigid monomers, GPCRs have shown an ever-increasing
flexibility in the number of intermolecular interactions they can participate in. Few rules can …

G-protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors in the human genome that respond to a plethora of signals, including …