Patients with a diverse spectrum of rare genetic disorders can present with inflammatory
bowel disease (monogenic IBD). Patients with these disorders often develop symptoms …

The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various
environmental and host (eg genetic-, epithelial-, immune and non-immune) factors are …

Inflammatory bowel disease (IBD) is a group of chronic multifactorial disorders. According to
a recent study, the number of IBD association loci is increased to 201, of which 37 and 27 …

Technological advances in the large scale analysis of human genetics have generated
profound insights into possible genetic contributions to chronic diseases including the …

Ulcerative colitis (UC) and Crohn's disease (CD) are related polygenic inflammatory bowel
diseases (IBDs), with distinct and overlapping susceptibility loci. Recently, hypothesis-free …

Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease
(IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …

The two major subtypes of inflammatory bowel disease (IBD), ulcerative colitis (UC, MIM#
191390) and Crohn's disease (CD, MIM# 266600), are chronic relapsing-remitting …

In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with
the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most …

Complex disease genetics has been revolutionised in recent years by the advent of genome-
wide association (GWA) studies. The chronic inflammatory bowel diseases (IBDs), Crohn's …