Clinical aspects and pathophysiology of inflammatory bowel disease
BA Hendrickson, R Gokhale… - Clinical microbiology …, 2002 - Am Soc Microbiol
The chronic inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are
recognized as important causes of gastrointestinal disease in children and adults. In this …
recognized as important causes of gastrointestinal disease in children and adults. In this …
Genetics of inflammatory bowel disease: progress and prospects
CG Mathew, CM Lewis - Human molecular genetics, 2004 - academic.oup.com
Strong epidemiological evidence for a genetic contribution to pathogenesis in inflammatory
bowel disease (IBD) has stimulated efforts to identify susceptibility genes for both of its major …
bowel disease (IBD) has stimulated efforts to identify susceptibility genes for both of its major …
Evolving paradigms in the pathogenesis of IBD
L Mayer - Journal of gastroenterology, 2010 - Springer
The pathogenesis of all immune-mediated inflammatory diseases has been carefully studied
over the past several decades, but it is only recently that we have come to appreciate …
over the past several decades, but it is only recently that we have come to appreciate …
Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
Background Multiple genes have been implicated by association studies in altering
inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more …
inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more …
Current status of genetics research in inflammatory bowel disease
S Vermeire, P Rutgeerts - Genes & Immunity, 2005 - nature.com
The research on genetic susceptibility of inflammatory bowel diseases (IBD) has been
tremendous and over 10 chromosomal regions have been identified by genome-wide …
tremendous and over 10 chromosomal regions have been identified by genome-wide …
Immunologic and molecular mechanisms in inflammatory bowel disease
MN Ince, DE Elliott - Surgical Clinics of North America, 2007 - Elsevier
Molecular and immunologic mechanisms underlying inflammation in inflammatory bowel
disease (IBD) are largely unknown. Recent studies have helped better characterize genetic …
disease (IBD) are largely unknown. Recent studies have helped better characterize genetic …
Mechanisms of pediatric inflammatory bowel disease
Inflammatory bowel disease (IBD), including Crohn disease and ulcerative colitis, is
characterized by chronic intestinal inflammation due to a complex interaction of genetic …
characterized by chronic intestinal inflammation due to a complex interaction of genetic …
[PDF][PDF] Mechanisms of disease
C Abraham, JH Cho - N Engl J Med, 2009 - jvsmedicscorner.com
The idiopathic inflammatory bowel diseases comprise two types of chronic intestinal
disorders: Crohn's disease and ulcerative colitis. Accumulating evidence suggests that …
disorders: Crohn's disease and ulcerative colitis. Accumulating evidence suggests that …