Long noncoding RNAs (lncRNAs) have emerged as prominent regulators of gene
expression in eukaryotes. The identification of lncRNA orthologs is essential in efforts to …

Long non-coding RNAs (lncRNAs) have emerged in recent years as major players in a
multitude of pathways across species, but it remains challenging to understand which of …

Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in
multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized …

The complex universe of RNA transcribed by mammalian cells includes thousands of large
RNA molecules that do not encode for proteins. Despite their lack of coding capacity and …

Background Recent advances in genomewide studies have revealed the abundance of long
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …

The recent advent of high-throughput approaches has revealed widespread transcription of
the human genome, leading to a new appreciation of transcription regulation, especially …

Like protein-coding genes, long noncoding RNA (lncRNA) genes are composed of introns
and exons. After their transcription, lncRNAs are subject to constitutive and/or alternative …

Over the last decade, long noncoding RNAs (lncRNAs) have emerged as a fundamental
molecular class whose members play pivotal roles in the regulation of the genome. The …

Recent transcriptome analyses have indicated that a large part of mammalian genomes are
transcribed into long non-protein-coding RNAs (lncRNAs). However, only a very small …

Large numbers of long RNAs with little or no protein-coding potential [long noncoding RNAs
(lncRNAs)] are being identified in eukaryotes. In parallel, increasing data describing the …