Cytokine storms in infectious diseases

JR Teijaro - Seminars in immunopathology, 2017 - Springer
The term Bcytokine storm^ has been adopted in the past several decades as a phrase to
describe the aberrant production of soluble mediators and the accompanying …

Cytokine storm and sepsis disease pathogenesis

BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
Infectious diseases are a leading cause of death worldwide. Sepsis is a severe clinical
syndrome related to the host response to infection. The severity of infections is due to an …

The meteorology of cytokine storms, and the clinical usefulness of this knowledge

IA Clark, B Vissel - Seminars in immunopathology, 2017 - Springer
The term cytokine storm has become a popular descriptor of the dramatic harmful
consequences of the rapid release of polypeptide mediators, or cytokines, that generate …

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
Cytokine storm is a phenomenon characterized by strong elevated circulating cytokines that
most often occur after an overreactive immune system is activated by an acute systemic …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
Immune cells secrete small protein molecules that aim for cell–cell communications. These
small molecules are called cytokines. Targeting cancer cells with administration of bispecific …

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
The cytokine storm has captured the attention of the public and the scientific community
alike, and while the general notion of an excessive or uncontrolled release of …

[PDF][PDF] Cytokines and sepsis: pathophysiology and therapy

L Shapiro, JA Gelfand - New Horiz, 1993 - researchgate.net
Sepsis is currently listed as the 13th leading cause of death in the United States, and it is on
the rise. Factors thought to account for this recent increase include an aging population …

Host–pathogen interactions in sepsis

T van der Poll, SM Opal - The Lancet infectious diseases, 2008 - thelancet.com
Sepsis is a major health problem. The concept that sepsis mortality is the result of an
uncontrolled hyperinflammatory host response has recently been challenged. It is now …

Weathering the storm: Improving therapeutic interventions for cytokine storm syndromes by targeting disease pathogenesis

LK Weaver, EM Behrens - Current treatment options in rheumatology, 2017 - Springer
Opinion statement Cytokine storm syndromes require rapid diagnosis and treatment to limit
the morbidity and mortality caused by the hyperinflammatory state that characterizes these …

The roles of neutrophils in cytokine storms

L Chan, N Karimi, S Morovati, K Alizadeh, JE Kakish… - Viruses, 2021 - mdpi.com
A cytokine storm is an abnormal discharge of soluble mediators following an inappropriate
inflammatory response that leads to immunopathological events. Cytokine storms can occur …