Yin and yang regulation of stress granules by Caprin-1
D Song, L Kuang, L Yang, L Wang… - Proceedings of the …, 2022 - National Acad Sciences
Stress granules (SGs) are cytoplasmic biomolecular condensates containing proteins and
RNAs in response to stress. Ras-GTPase–activating protein binding protein 1 (G3BP1) is a …
RNAs in response to stress. Ras-GTPase–activating protein binding protein 1 (G3BP1) is a …
Stress granules and neurodegeneration
Recent advances suggest that the response of RNA metabolism to stress has an important
role in the pathophysiology of neurodegenerative diseases, particularly amyotrophic lateral …
role in the pathophysiology of neurodegenerative diseases, particularly amyotrophic lateral …
[HTML][HTML] ATPase-modulated stress granules contain a diverse proteome and substructure
Stress granules are mRNA-protein granules that form when translation initiation is limited,
and they are related to pathological granules in various neurodegenerative diseases. Super …
and they are related to pathological granules in various neurodegenerative diseases. Super …
[HTML][HTML] TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
Autophagy, a homeostatic process whereby eukaryotic cells target cytoplasmic cargo for
degradation, plays a broad role in health and disease states. Here we screened the TRIM …
degradation, plays a broad role in health and disease states. Here we screened the TRIM …
A new phase of networking: the molecular composition and regulatory dynamics of mammalian stress granules
SR Millar, JQ Huang, KJ Schreiber, YC Tsai… - Chemical …, 2023 - ACS Publications
Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …
[HTML][HTML] TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells
Autophagy is one of the cellular adaptive processes that provide protection against many
pathological conditions like infection, cancer, neurodegeneration, and aging. Recent …
pathological conditions like infection, cancer, neurodegeneration, and aging. Recent …
[HTML][HTML] Role of the ubiquitin system in stress granule metabolism
N Tolay, A Buchberger - International Journal of Molecular Sciences, 2022 - mdpi.com
Eukaryotic cells react to various stress conditions with the rapid formation of membrane-less
organelles called stress granules (SGs). SGs form by multivalent interactions between RNAs …
organelles called stress granules (SGs). SGs form by multivalent interactions between RNAs …
Mammalian stress granules and P bodies at a glance
Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-
based cellular compartments that assemble in response to stress. SGs and PBs form …
based cellular compartments that assemble in response to stress. SGs and PBs form …
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine
Macroautophagy/autophagy is an essential process for cellular survival and is implicated in
many diseases. A critical step in autophagy is the transport of the transcription factor TFEB …
many diseases. A critical step in autophagy is the transport of the transcription factor TFEB …
HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency
SM Guilbert, H Lambert, MA Rodrigue… - The FASEB …, 2018 - Wiley Online Library
BCL2‐associated athanogene (BAG)‐3 is viewed as a platform that would physically and
functionally link distinct classes of molecular chaperones of the heat shock protein (HSP) …
functionally link distinct classes of molecular chaperones of the heat shock protein (HSP) …