Inorganic hydrogen polysulfides: chemistry, chemical biology and detection

H Liu, MN Radford, C Yang, W Chen… - British journal of …, 2019 - Wiley Online Library
Recent studies suggest that inorganic hydrogen polysulfides (H2Sn, n≥ 2) play important
regulatory roles in redox biology. Modulation of their cellular levels could have potential …

[HTML][HTML] Redox chemistry and chemical biology of H2S, hydropersulfides, and derived species: implications of their possible biological activity and utility

K Ono, T Akaike, T Sawa, Y Kumagai, DA Wink… - Free Radical Biology …, 2014 - Elsevier
Hydrogen sulfide (H 2 S) is an endogenously generated and putative signaling/effector
molecule. Despite its numerous reported functions, the chemistry by which it elicits its …

Polysulfides in biology: From intricate chemistry to an astonishing yet hidden biological activity

EC Estevam, L Faulstich, S Griffin… - Current Organic …, 2016 - ingentaconnect.com
The last decade has witnessed a growing interest in natural and synthetic polysulfanes and
their potential uses in Medicine and Agriculture. Whilst the chemistry and biochemistry of …

Signaling molecules: hydrogen sulfide and polysulfide

H Kimura - Antioxidants & redox signaling, 2015 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as a signaling molecule
as well as a cytoprotectant. It modulates neurotransmission, regulates vascular tone, and …

The development of fluorescent probes for visualizing intracellular hydrogen polysulfides

W Chen, EW Rosser, T Matsunaga… - Angewandte …, 2015 - Wiley Online Library
Endogenous hydrogen polysulfides (H2Sn; n> 1) have been recognized as important
regulators in sulfur‐related redox biology. H2Sn can activate tumor suppressors, ion …

The reaction of hydrogen sulfide with disulfides: formation of a stable trisulfide and implications for biological systems

CL Bianco, T Akaike, T Ida, P Nagy… - British Journal of …, 2019 - Wiley Online Library
Background and Purpose The signalling associated with hydrogen sulfide (H2S) remains to
be established, and recent studies have alluded to the possibility that H2S‐derived species …

A near-infrared fluorescent probe for the detection of hydrogen polysulfides biosynthetic pathways in living cells and in vivo

M Gao, R Wang, F Yu, J You, L Chen - Analyst, 2015 - pubs.rsc.org
Hydrogen polysulfides (H2Sn, n> 1), derived from hydrogen sulfide (H2S), have been
considered to be involved in cytoprotective processes and redox signaling. The emerging …

Signalling by hydrogen sulfide and polysulfides via protein S‐sulfuration

H Kimura - British journal of pharmacology, 2020 - Wiley Online Library
Hydrogen sulfide (H2S) is a signalling molecule that regulates neuronal transmission,
vascular tone, cytoprotection, inflammatory responses, angiogenesis, and oxygen sensing …

[HTML][HTML] Effects of sulfane sulfur content in benzyl polysulfides on thiol-triggered H2S release and cell proliferation

SG Bolton, MM Cerda, AK Gilbert, MD Pluth - Free Radical Biology and …, 2019 - Elsevier
Investigations into hydrogen sulfide (H 2 S) signaling pathways have demonstrated both the
generation and importance of persulfides, which are reactive sulfur species that contain both …

[HTML][HTML] The physiological role of hydrogen sulfide and beyond

H Kimura - Nitric oxide, 2014 - Elsevier
Hydrogen sulfide (H 2 S) has been considered to be a physiological mediator since the
identification of endogenous sulfides in the mammalian brain. H 2 S is produced from l …