Motivation Single-cell RNA sequencing (scRNA-seq) techniques have revolutionized the investigation of transcriptomic landscape in individual cells. Recent advancements in spatial …
X Li, C Xiao, J Qi, W Xue, X Xu, Z Mu… - Nucleic acids …, 2023 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) provides insights into gene expression heterogeneities in diverse cell types underlying homeostasis, development and pathological …
Z Zhang, F Cui, W Su, L Dou, A Xu, C Cao… - Bioinformatics, 2022 - academic.oup.com
Integrative analysis of single-cell RNA-sequencing (scRNA-seq) data with spatial data for the same species and organ would provide each cell sample with a predictive spatial …
Single-cell technologies are emerging fast due to their ability to unravel the heterogeneity of biological systems. While scRNA-seq is a powerful tool that measures whole-transcriptome …
X Shi, Y Yang, X Ma, Y Zhou, Z Guo… - Nucleic Acids …, 2023 - academic.oup.com
In the analysis of both single-cell RNA sequencing (scRNA-seq) and spatially resolved transcriptomics (SRT) data, classifying cells/spots into cell/domain types is an essential …
W Yin, X Wu, L Chen, Y Wan, Y Zhou - Small Science, 2024 - Wiley Online Library
Accurate mapping between single‐cell RNA sequencing (scRNA‐seq) and low‐resolution spatial transcriptomics (ST) data compensates for both limited resolution of ST data and …
Since many single-cell RNA-seq (scRNA-seq) data are obtained after cell sorting, such as when investigating immune cells, tracking cellular landscape by integrating single-cell data …
L Wang, Y Hu, L Gao - Briefings in Bioinformatics, 2024 - academic.oup.com
Most sequencing-based spatial transcriptomics (ST) technologies do not achieve single-cell resolution where each captured location (spot) may contain a mixture of cells from …