Genetic characteristics and phylogenetic analysis of Brazilian clinical strains of Pseudomonas aeruginosa harboring CRISPR/Cas systems

AC de Oliveira Luz, WJ da Silva Junior… - Current Genetics, 2021 - Springer
The CRISPR–Cas are adaptive immune systems found in archaea and bacteria, responsible
for providing sequence-specific resistance against foreign DNA. Strains of Pseudomonas …

Analysis of direct repeats and spacers of CRISPR/Cas systems type IF in Brazilian clinical strains of Pseudomonas aeruginosa

ACO Luz, JMA da Silva, AM Rezende… - Molecular Genetics and …, 2019 - Springer
CRISPR/Cas is an adaptive immune system found in prokaryotes, with the main function of
protecting these cells from invasion and possible death by mobile genetic elements …

Novel PCR detection of CRISPR/Cas systems in Pseudomonas aeruginosa and its correlation with antibiotic resistance

M Soliman, HS Said, M El-Mowafy, R Barwa - Applied Microbiology and …, 2022 - Springer
CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-
associated proteins) systems are considered as acquired immune mechanisms in Gram …

Prevalence and analysis of CRISPR/Cas systems in Pseudomonas aeruginosa isolates from Greece

LA Gagaletsios, CC Papagiannitsis… - Molecular Genetics and …, 2022 - Springer
The objective of this study was to investigate the prevalence of CRISPR/Cas systems in P.
aeruginosa, isolated from a Greek hospital. Additionally, we aimed to determine the origin of …

Phylogenetic distribution of CRISPR-Cas systems in antibiotic-resistant Pseudomonas aeruginosa

A van Belkum, LB Soriaga, MC LaFave, S Akella… - MBio, 2015 - Am Soc Microbiol
Pseudomonas aeruginosa is an antibiotic-refractory pathogen with a large genome and
extensive genotypic diversity. Historically, P. aeruginosa has been a major model system for …

Exploring the success of Brazilian endemic clone Pseudomonas aeruginosa ST277 and its association with the CRISPR-Cas system type IC

MC Silveira, CM Rocha-de-Souza, RM Albano… - BMC genomics, 2020 - Springer
Abstract Background The Brazilian endemic clone Pseudomonas aeruginosa ST277 carries
important antibiotic resistance determinants, highlighting the gene coding for SPM-1 …

CRISPR-cas systems in bacteria and archaea

M Kamruzzaman, A Yan… - Frontiers in Microbiology, 2022 - frontiersin.org
The CRISPR-Cas [clustered regularly interspaced short palindromic repeats and the
CRISPR-associated genes (Cas)] is an adaptive immune system of prokaryotes against the …

Genome-wide correlation analysis suggests different roles of CRISPR-Cas systems in the acquisition of antibiotic resistance genes in diverse species

S Shehreen, T Chyou, PC Fineran… - … Transactions of the …, 2019 - royalsocietypublishing.org
CRISPR-Cas systems are widespread in bacterial and archaeal genomes, and in their
canonical role in phage defence they confer a fitness advantage. However, CRISPR-Cas …

Characterization of CRISPR-Cas Systems in Clinical Klebsiella pneumoniae Isolates Uncovers Its Potential Association With Antibiotic Susceptibility

HY Li, CY Kao, WH Lin, PX Zheng, JJ Yan… - Frontiers in …, 2018 - frontiersin.org
Prokaryotic CRISPR-Cas systems limit the acquisition of genetic elements and provide
immunity against invasive bacteriophage. The characteristics of CRISPR-Cas systems in …

Analysis of CRISPR/Cas Genetic Structure, Spacer Content and Molecular Epidemiology in Brazilian Acinetobacter baumannii Clinical Isolates

AMA Silva, ACO Luz, KVM Xavier, MPS Barros… - Pathogens, 2023 - mdpi.com
CRISPR/Cas is a molecular mechanism to prevent predatory viruses from invading bacteria
via the insertion of small viral sequences (spacers) in its repetitive locus. The nature of …